Effects of particulate air pollution on the respiratory health of subjects who live in three areas in Kanpur, India.

Mukesh Sharma, V Narendra Kumar, Subodh K Katiyar, Richa Sharma, Bhanu P Shukla, Babu Sengupta
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引用次数: 32

Abstract

In this study, the authors assessed the relationship between daily changes in respiratory health and particulate levels with diameters of (a) less than 10 microm (PM10) and (b) less than 2.5 microm (PM2.5) in Kanpur, India. The subjects (N = 91) were recruited from 3 areas in Kanpur: (1) Indian Institute of Technology (Kanpur), which was a relatively clean area; (b) Vikas Nagar, a typical commercial area; and (c) finally, the residential area of Juhilal Colony. All subjects resided near to air quality monitoring sites. Air quality and peak expiratory flow rate samplings were conducted for 39 d. Once during the sampling period, lung-function tests (i.e., forced expiratory volume in 1 s, forced vital capacity) were performed on each subject. Subjects who resided at the clean site performed at predicted (i.e., acceptable) values more often than did subjects who lived at the remaining 2 sites. Subjects who lived at all 3 sites demonstrated a substantial average deficit in baseline forced vital capacity and forced expiratory volume in 1 s values. The authors used a statistical model to estimate that an increase of 100 microg/m3 of the pollutant PM10 could reduce the mean peak expiratory flow rate of an individual by approximately 3.2 l/min.

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空气微粒污染对居住在印度坎普尔三个地区的受试者呼吸健康的影响。
在这项研究中,作者评估了印度坎普尔呼吸健康的每日变化与直径(a)小于10微米(PM10)和(b)小于2.5微米(PM2.5)的颗粒水平之间的关系。研究对象(N = 91)从坎普尔3个地区招募:(1)印度理工学院(坎普尔),这是一个相对清洁的地区;(b)维卡斯纳加尔,一个典型的商业区;(c)最后是Juhilal殖民地的住宅区。所有研究对象都居住在空气质量监测点附近。空气质量和呼气峰值流速采样进行了39 d。在采样期间,对每个受试者进行一次肺功能测试(即1 s内的用力呼气量,用力肺活量)。居住在干净地点的受试者比居住在其余两个地点的受试者更经常达到预测(即可接受)值。生活在所有3个地点的受试者在基线用力肺活量和用力呼气量上均表现出显著的平均缺陷。作者使用统计模型估计,污染物PM10每增加100微克/立方米,个体的平均呼气流速峰值就会降低约3.2升/分钟。
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