Visible deformity in childhood leprosy--a 10-year study.

Bikash Ranjan Kar, C K Job
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Abstract

Deformity seen in children with leprosy has not often been studied, as the disease itself is less common in children. Deformity, being synonymous with the stigma of leprosy, is a definite social problem in children. In this study we have focused on the burden of deformity in children with leprosy, and various factors responsible for the deformities are discussed. We have observed an incidence of 10.5% of Grade II deformities in children with leprosy, which is very high compared to the community rate of 1.4%. Various factors which contributed significantly to the deformities in our study were: increasing age of children, delay in accessing health care, multiple skin lesions, multibacillary disease, smear positivity, multiple nerve involvement, and reaction at the time of presentation to the hospital. Logistic regression analysis showed that children with thickened nerve trunks had 6.1 times higher risk of developing deformities compared to those who did not have nerve enlargement. Children with the above risk factors should be followed up more frequently so as to detect any deformity as early as possible.

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儿童麻风病的可见畸形——一项为期10年的研究。
由于麻风病本身在儿童中不太常见,因此对麻风病儿童的畸形研究并不多见。残疾与麻风病的耻辱同义,是儿童的一个明确的社会问题。在这项研究中,我们关注的是麻风病儿童的畸形负担,并讨论了导致畸形的各种因素。我们观察到麻风病儿童II级畸形发生率为10.5%,与社区发生率1.4%相比非常高。在我们的研究中,对畸形有显著影响的各种因素是:儿童年龄的增长、获得医疗保健的延迟、多发性皮肤病变、多细菌疾病、涂片阳性、多神经受累以及就诊时的反应。Logistic回归分析显示,神经干增粗的儿童发生畸形的风险是没有神经增大的儿童的6.1倍。有上述危险因素的儿童应更频繁地随访,以便尽早发现任何畸形。
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Visible deformity in childhood leprosy--a 10-year study. Close contacts with leprosy in newly diagnosed leprosy patients in a high and low endemic area: comparison between Bangladesh and Thailand. Factors contributing to the decline of leprosy in Spain in the second half of the twentieth century. Study of apoptosis in skin lesions of leprosy in relation to treatment and lepra reactions. Myiasis in leprosy.
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