[Normalisation of contralateral adrenal function after long-term mitotane therapy in a girl after surgical treatment of adrenocortical carcinoma].

Agnieszka Lecka, Maria Ginalska-Malinowska
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Abstract

The main method of treatment of adrenocortical tumours is surgery. The efficacy of the mitotane therapy is still controversial with many serious side effects of the therapy. Moreover, patients receiving mitotane should be carefully monitored for adrenal insufficiency and usually require long-term hormone replacement therapy. We present a rare case of normalisation of the contralateral adrenal function after long-term mitotane therapy as a post-surgical treatment of the adrenocortical tumour.

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[1例女孩肾上腺皮质癌术后长期米托坦治疗后对侧肾上腺功能恢复正常]。
治疗肾上腺皮质肿瘤的主要方法是手术。米托坦治疗的疗效仍有争议,治疗有许多严重的副作用。此外,接受米托坦治疗的患者应仔细监测肾上腺功能不全,通常需要长期激素替代治疗。我们提出了一个罕见的情况下,长期米托坦治疗后,对侧肾上腺功能的正常化作为一个术后治疗肾上腺皮质肿瘤。
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