[Thyroid volume evaluation in girls with Turner syndrome according to normal range for healthy population].

Anna M Kucharska, Michał Brzewski, Barbara Czarnocka, Aleksandra Januszek-Trzciakowska, Barbara Rymkiewicz-Kluczyńska
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Abstract

Introduction: Turner syndrome is a common chromosomal aberration. Among other features of that syndrome susceptibility to autoimmune diseases is well known. Most often there is Hashimoto's thyroiditis. Because of short stature the evaluation of thyroid volume according to chronological age seems to be not efficient. THE AIM of the study was to find an adequate method of thyroid volume evaluation in girls with Turner syndrome using standards for healthy children.

Material and methods: 54 girls with Turner syndrome were examined, mean age was 11 years and 9 months. Physical and ultrasonographic examination of thyroid gland was performed. The hormonal state and presence of antithyroid autoantibodies were evaluated. The thyroid volume was evaluated according to normal range (by Delange) for chronological and height age of each girl.

Results: According to chronological age the thyroid volume was in normal range, but according to height age in 3 patients the thyroid volume was over 97 percentile. They were the same girls in whom we detected goiter according to physical examination.

Conclusions: We suggest that proposed method gives the possibility of an accurate evaluation of thyroid volume in patients with Turner syndrome and in other patients with growth deficiency.

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[按健康人群正常范围评价特纳综合征女童甲状腺体积]。
特纳综合征是一种常见的染色体畸变。在该综合征的其他特征中,对自身免疫性疾病的易感性是众所周知的。最常见的是桥本甲状腺炎。由于身材矮小,根据年龄对甲状腺体积的评估似乎不太有效。本研究的目的是利用健康儿童的标准,寻找一种适合特纳综合征女童甲状腺体积评估的方法。材料与方法:对54例特纳综合征女童进行检查,平均年龄11岁9个月。行甲状腺物理及超声检查。评估激素状态和抗甲状腺自身抗体的存在。甲状腺体积按正常范围(Delange法)测定年龄和年龄。结果:3例患者按实足年龄甲状腺体积在正常范围内,按身高年龄甲状腺体积在97%以上。她们就是我们在体检中发现甲状腺肿大的那些女孩。结论:我们认为所提出的方法为特纳综合征患者和其他生长缺陷患者提供了准确评估甲状腺体积的可能性。
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