{"title":"Translational control of long-term synaptic plasticity and memory storage by eIF2alpha.","authors":"Mauro Costa-Mattioli, Nahum Sonenberg","doi":"10.1615/critrevneurobiol.v18.i1-2.190","DOIUrl":null,"url":null,"abstract":"Both long-lasting changes in synaptic function and long-term memory require gene expression. However, the molecular mechanisms by which gene expression is turned on are not fully understood. In this review, we highlight the role of the eukaryotic initiation factor 2 alpha (eIF2alpha) signalling pathway in long-term synaptic plasticity and memory.","PeriodicalId":10778,"journal":{"name":"Critical reviews in neurobiology","volume":"18 1-2","pages":"187-95"},"PeriodicalIF":0.0000,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"21","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Critical reviews in neurobiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1615/critrevneurobiol.v18.i1-2.190","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 21
Abstract
Both long-lasting changes in synaptic function and long-term memory require gene expression. However, the molecular mechanisms by which gene expression is turned on are not fully understood. In this review, we highlight the role of the eukaryotic initiation factor 2 alpha (eIF2alpha) signalling pathway in long-term synaptic plasticity and memory.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
