Facile and General Method for Synthesis of Sugar Coated Gold Nanoparticles.

Kavita K Katti, Vijaya Kattumuri, Sharanya Bhaskaran, Kattesh V Katti, Raghuraman Kannan
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Abstract

This letter describes a general method for the preparation of carbohydrate coated gold nanoparticles. The generality of this method has been demonstrated by surface coating AuNPs with the following sugars: glucose (monosaccharide); sucrose, maltose, or lactose (disaccharides); raffinose (trisaccharide); and starch (polysaccharide). The non-toxic, water-soluble phosphino aminoacid P(CH(2)NHCH(CH(3)-)COOH)(3), THPAL, has been used as a reducing agent in this process. The sizes of sugar coated AuNPs that have been generated in this study are: 30 ± 8 nm (Glucose), 10 ± 6 nm (sucrose), 8 ± 2 nm (maltose), 3 ± 1 nm (lactose), 6 ± 2 nm (raffinose), and 39 ± 9 nm (starch).

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合成糖包金纳米粒子的简便通用方法
这封信介绍了一种制备碳水化合物涂层金纳米粒子的通用方法。通过在 AuNPs 表面涂覆以下糖类,证明了该方法的通用性:葡萄糖(单糖);蔗糖、麦芽糖或乳糖(二糖);棉子糖(三糖);以及淀粉(多糖)。在这一过程中,无毒的水溶性膦基氨基酸 P(CH(2)NHCH(CH(3)-)COOH)(3) THPAL 被用作还原剂。本研究生成的糖衣 AuNPs 的尺寸为30 ± 8 nm(葡萄糖)、10 ± 6 nm(蔗糖)、8 ± 2 nm(麦芽糖)、3 ± 1 nm(乳糖)、6 ± 2 nm(棉子糖)和 39 ± 9 nm(淀粉)。
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