Deborah J. Wexler , Catherine C. Beauharnais , Susan Regan , David M. Nathan , Enrico Cagliero , Mary E. Larkin
{"title":"Impact of inpatient diabetes management, education, and improved discharge transition on glycemic control 12 months after discharge","authors":"Deborah J. Wexler , Catherine C. Beauharnais , Susan Regan , David M. Nathan , Enrico Cagliero , Mary E. Larkin","doi":"10.1016/j.diabres.2012.09.016","DOIUrl":null,"url":null,"abstract":"<div><h3>Aim</h3><p><span>To determine whether inpatient diabetes management and education with improved transition to outpatient care<span> (IDMET) improves glycemic control after hospital discharge </span></span>in patients with uncontrolled type 2 diabetes (T2DM).</p></div><div><h3>Methods</h3><p><span><span>Adult inpatients with T2DM and </span>HbA1c</span> <!-->><!--> <!-->7.5% (58<!--> <!-->mmol/mol) admitted for reasons other than diabetes to an academic medical center were randomly assigned to either IDMET or usual care (UC). Linear mixed models estimated treatment-dependent differences in the change in HbA1c (measured at 3, 6, and 12 months) from baseline to 1-year follow-up.</p></div><div><h3>Results</h3><p>Thirty-one subjects had mean age 55<!--> <!-->±<!--> <!-->12.6 years, with mean HbA1c of 9.7<!--> <!-->±<!--> <!-->1.6% (82<!--> <!-->±<!--> <!-->18<!--> <!-->mmol/mol). Mean inpatient glucose was lower in the IDMET than in the UC group (176<!--> <!-->±<!--> <!-->66 versus 195<!--> <!-->±<!--> <!-->74<!--> <!-->mg/dl [9.7 versus 10.8<!--> <!-->mmol/l], <em>P</em> <!-->=<!--> <span>0.001). In the year after discharge, the average HbA1c reduction was greater in the IDMET group compared with the UC group by 0.6% (SE 0.5%, [7 (SE 5)</span> <!-->mmol/mol], <em>P</em> <!-->=<!--> <!-->0.3). Among patients newly discharged on insulin, the average HbA1c reduction was greater in the in the IDMET group than in the UC group by 2.4% (SE 1.0%, [25 (SE 11)<!--> <!-->mmol/mol], <em>P</em> <!-->=<!--> <!-->0.04).</p></div><div><h3>Conclusions</h3><p>Inpatient diabetes management (IDMET) substantially improved glycemic control 1 year after discharge in patients newly discharged on insulin; patients previously treated with insulin did not benefit.</p></div>","PeriodicalId":11249,"journal":{"name":"Diabetes research and clinical practice","volume":"98 2","pages":"Pages 249-256"},"PeriodicalIF":7.4000,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.diabres.2012.09.016","citationCount":"74","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diabetes research and clinical practice","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0168822712003208","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 74
Abstract
Aim
To determine whether inpatient diabetes management and education with improved transition to outpatient care (IDMET) improves glycemic control after hospital discharge in patients with uncontrolled type 2 diabetes (T2DM).
Methods
Adult inpatients with T2DM and HbA1c > 7.5% (58 mmol/mol) admitted for reasons other than diabetes to an academic medical center were randomly assigned to either IDMET or usual care (UC). Linear mixed models estimated treatment-dependent differences in the change in HbA1c (measured at 3, 6, and 12 months) from baseline to 1-year follow-up.
Results
Thirty-one subjects had mean age 55 ± 12.6 years, with mean HbA1c of 9.7 ± 1.6% (82 ± 18 mmol/mol). Mean inpatient glucose was lower in the IDMET than in the UC group (176 ± 66 versus 195 ± 74 mg/dl [9.7 versus 10.8 mmol/l], P = 0.001). In the year after discharge, the average HbA1c reduction was greater in the IDMET group compared with the UC group by 0.6% (SE 0.5%, [7 (SE 5) mmol/mol], P = 0.3). Among patients newly discharged on insulin, the average HbA1c reduction was greater in the in the IDMET group than in the UC group by 2.4% (SE 1.0%, [25 (SE 11) mmol/mol], P = 0.04).
Conclusions
Inpatient diabetes management (IDMET) substantially improved glycemic control 1 year after discharge in patients newly discharged on insulin; patients previously treated with insulin did not benefit.
期刊介绍:
Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.