Impact of inpatient diabetes management, education, and improved discharge transition on glycemic control 12 months after discharge

IF 7.4 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetes research and clinical practice Pub Date : 2012-11-01 DOI:10.1016/j.diabres.2012.09.016
Deborah J. Wexler , Catherine C. Beauharnais , Susan Regan , David M. Nathan , Enrico Cagliero , Mary E. Larkin
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引用次数: 74

Abstract

Aim

To determine whether inpatient diabetes management and education with improved transition to outpatient care (IDMET) improves glycemic control after hospital discharge in patients with uncontrolled type 2 diabetes (T2DM).

Methods

Adult inpatients with T2DM and HbA1c > 7.5% (58 mmol/mol) admitted for reasons other than diabetes to an academic medical center were randomly assigned to either IDMET or usual care (UC). Linear mixed models estimated treatment-dependent differences in the change in HbA1c (measured at 3, 6, and 12 months) from baseline to 1-year follow-up.

Results

Thirty-one subjects had mean age 55 ± 12.6 years, with mean HbA1c of 9.7 ± 1.6% (82 ± 18 mmol/mol). Mean inpatient glucose was lower in the IDMET than in the UC group (176 ± 66 versus 195 ± 74 mg/dl [9.7 versus 10.8 mmol/l], P = 0.001). In the year after discharge, the average HbA1c reduction was greater in the IDMET group compared with the UC group by 0.6% (SE 0.5%, [7 (SE 5) mmol/mol], P = 0.3). Among patients newly discharged on insulin, the average HbA1c reduction was greater in the in the IDMET group than in the UC group by 2.4% (SE 1.0%, [25 (SE 11) mmol/mol], P = 0.04).

Conclusions

Inpatient diabetes management (IDMET) substantially improved glycemic control 1 year after discharge in patients newly discharged on insulin; patients previously treated with insulin did not benefit.

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住院糖尿病管理、教育和改善出院过渡期对出院后12个月血糖控制的影响
目的探讨住院糖尿病管理和教育(IDMET)是否能改善未控制的2型糖尿病(T2DM)患者出院后的血糖控制。方法对住院的成年T2DM合并HbA1c患者;7.5% (58 mmol/mol)因非糖尿病原因入住学术医疗中心,随机分配到IDMET或常规护理(UC)组。线性混合模型估计了从基线到1年随访期间HbA1c变化的治疗依赖性差异(在3、6和12个月测量)。结果31例患者平均年龄55±12.6岁,平均HbA1c为9.7±1.6%(82±18 mmol/mol)。IDMET组平均住院血糖低于UC组(176±66 vs 195±74 mg/dl [9.7 vs 10.8 mmol/l], P = 0.001)。出院后一年,IDMET组的平均HbA1c降幅比UC组大0.6% (SE 0.5%, [7 (SE 5) mmol/mol], P = 0.3)。在新出院的胰岛素治疗患者中,IDMET组的平均HbA1c降低量比UC组高2.4% (SE 1.0%, [25 (SE 11) mmol/mol], P = 0.04)。结论患者糖尿病管理(IDMET)可显著改善胰岛素治疗新出院患者出院后1年的血糖控制;先前接受胰岛素治疗的患者没有获益。
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来源期刊
Diabetes research and clinical practice
Diabetes research and clinical practice 医学-内分泌学与代谢
CiteScore
10.30
自引率
3.90%
发文量
862
审稿时长
32 days
期刊介绍: Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.
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