Tanya L Alderete, Lauren E Gyllenhammer, Courtney E Byrd-Williams, Donna Spruijt-Metz, Michael I Goran, Jaimie N Davis
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引用次数: 0
Abstract
This study assessed the changes in time spent in moderate to vigorous physical activity (MVPA) on fat depots, insulin action, and inflammation. Longitudinal data were generated from 66 Hispanic adolescents (15.6±1.1 yr; BMI percentile 97.1±3.0) who participated in a 16-wk nutrition or nutrition+exercise intervention. There were no effects of the intervention on PA, but there were inter-individual changes in PA. For purposes of this analysis, all intervention groups were combined to assess how changes in PA during 16 wk affected changes in adiposity, insulin action, and markers of inflammation. MVPA was assessed by 7-day accelerometry, total body fat via DXA, liver fat by MRI, and insulin, glucose and HOMA-IR via a fasting blood draw. A repeated measures ANCOVA was used to assess the effect of MVPA on fat depots, insulin action, and inflammatory markers. Sixty-two percent of participants increased MVPA (mean increase, 19.7±16.5 min/day) and 38% decreased MVPA (mean decrease, 10.7±10.1 min/day). Those who increased MVPA by as little as 20 min per day over 16 wk, compared to those who decreased MVPA, had significant reductions in liver fat (-13% vs. +3%; P=0.01), leptin levels (-18% vs. +4%; P=0.02), and fasting insulin (-23% vs. +5%; P=0.05). These findings indicate that a modest increase in MVPA can improve metabolic health in sedentary overweight Hispanic adolescents.
这项研究评估了中度到剧烈体育活动(MVPA)对脂肪储备、胰岛素作用和炎症的影响。纵向数据来自66名西班牙裔青少年(15.6±1.1岁;BMI百分位数97.1±3.0),参加16周营养或营养+运动干预。干预对PA没有影响,但个体间PA有变化。为了进行分析,我们将所有干预组结合起来,评估16周内PA的变化如何影响肥胖、胰岛素作用和炎症标志物的变化。通过7天加速度计评估MVPA,通过DXA评估全身脂肪,通过MRI评估肝脏脂肪,通过空腹抽血评估胰岛素、葡萄糖和HOMA-IR。使用重复测量ANCOVA来评估MVPA对脂肪库、胰岛素作用和炎症标志物的影响。62%的参与者MVPA增加(平均增加19.7±16.5分钟/天),38%的参与者MVPA减少(平均减少10.7±10.1分钟/天)。那些在16周内每天增加MVPA仅20分钟的患者,与那些减少MVPA的患者相比,肝脏脂肪显著减少(-13% vs. +3%;P=0.01),瘦素水平(-18% vs. +4%;P=0.02),空腹胰岛素(-23% vs. +5%;P = 0.05)。这些发现表明,适度增加MVPA可以改善久坐超重的西班牙裔青少年的代谢健康。
期刊介绍:
The Journal of Exercise Physiologyonline, published by the American Society of Exercise Physiologists, is a professional peer reviewed Internet-based journal devoted to original research in exercise physiology. The journal is directed by the Editor-In-Chief with supporting editorial assistance via Associate Editors knowledgeable in the field of exercise physiology. JEPonline is the first electronic peer reviewed exercise physiology journal in the history of the profession.