Quantum-like model for the adaptive dynamics of the genetic regulation of E. coli's metabolism of glucose/lactose.

Systems and Synthetic Biology Pub Date : 2012-06-01 Epub Date: 2012-04-11 DOI:10.1007/s11693-012-9091-1
Masanari Asano, Irina Basieva, Andrei Khrennikov, Masanori Ohya, Yoshiharu Tanaka, Ichiro Yamato
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引用次数: 35

Abstract

We developed a quantum-like model describing the gene regulation of glucose/lactose metabolism in a bacterium, Escherichia coli. Our quantum-like model can be considered as a kind of the operational formalism for microbiology and genetics. Instead of trying to describe processes in a cell in the very detail, we propose a formal operator description. Such a description may be very useful in situation in which the detailed description of processes is impossible or extremely complicated. We analyze statistical data obtained from experiments, and we compute the degree of E. coli's preference within adaptive dynamics. It is known that there are several types of E. coli characterized by the metabolic system. We demonstrate that the same type of E. coli can be described by the well determined operators; we find invariant operator quantities characterizing each type. Such invariant quantities can be calculated from the obtained statistical data.

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大肠杆菌葡萄糖/乳糖代谢遗传调控自适应动力学的类量子模型。
我们开发了一个类似量子的模型来描述细菌中葡萄糖/乳糖代谢的基因调控,大肠杆菌。我们的类量子模型可以看作是微生物学和遗传学的一种操作形式。我们提出了一种正式的算子描述,而不是试图非常详细地描述单元中的过程。在不可能或极其复杂地详细描述过程的情况下,这种描述可能非常有用。我们分析了从实验中获得的统计数据,并计算了大肠杆菌在适应动力学中的偏好程度。众所周知,有几种类型的大肠杆菌以代谢系统为特征。我们证明了同一类型的大肠杆菌可以用确定的操作符来描述;我们找到表征每种类型的不变算子量。这些不变量可以从得到的统计数据中计算出来。
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