The Association between Alcohol Dependence and Depression before and after Treatment for Alcohol Dependence.

ISRN Psychiatry Pub Date : 2012-01-26 Print Date: 2012-01-01 DOI:10.5402/2012/482802

Mary W Kuria, David M Ndetei, Isodore S Obot, Lincoln I Khasakhala, Betty M Bagaka, Margaret N Mbugua, Judy Kamau

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Abstract

The presence of depression in alcohol-dependent persons is likely to influence treatment process and outcomes. Identification of depression is important though not every depressed alcohol-dependent person requires treatment with antidepressants. Understanding the association between depression and alcohol dependence is essential for proper management of alcohol dependence. Objectives. To determine the prevalence of depression among alcohol-dependent persons before and after alcohol detoxification and rehabilitation. Design. Clinical trial with pre-/postmeasurements. Method. The CIDI and WHO-ASSIST were administered to 188 alcohol-dependent persons at intake and after six months. A researcher-designed sociodemographic questionnaire was also administered at intake. Results. The prevalence of depression among alcohol-dependent persons is high (63.8%) with a significant association between depression and the mean AUDIT score. At posttest, depressed participants had a statistically significant craving for alcohol. Conclusion. Alcohol dependence is associated with major depression.

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酒精依赖症治疗前后酒精依赖症与抑郁症之间的关系。

酒精依赖者是否患有抑郁症可能会影响治疗过程和结果。尽管并非每个抑郁的酒精依赖者都需要接受抗抑郁药物治疗，但识别抑郁症非常重要。了解抑郁与酒精依赖之间的关系对于正确处理酒精依赖至关重要。研究目的确定酒精依赖者在戒酒和康复前后抑郁症的患病率。设计。进行前/后测量的临床试验。方法。对188名酒精依赖者在入院时和6个月后进行CIDI和WHO-ASSIST测试。入院时还进行了研究人员设计的社会人口学问卷调查。结果显示酒精依赖者中抑郁症的发病率很高（63.8%），抑郁症与 AUDIT 平均得分之间存在显著关联。在测试后，抑郁参与者对酒精的渴望程度在统计学上具有显著性。结论酒精依赖与重度抑郁有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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ISRN Psychiatry

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