Self-reported low physical function is associated with diabetes mellitus and insulin resistance in HIV-positive and HIV-negative men.

Future HIV therapy Pub Date : 2008-11-01 DOI:10.2217/17469600.2.6.539

Allison Longenberger, Jeong Youn Lim, Trevor Orchard, Maria Mori Brooks, Jennifer Brach, Kristen Mertz, Lawrence A Kingsley

{"title":"Self-reported low physical function is associated with diabetes mellitus and insulin resistance in HIV-positive and HIV-negative men.","authors":"Allison Longenberger, Jeong Youn Lim, Trevor Orchard, Maria Mori Brooks, Jennifer Brach, Kristen Mertz, Lawrence A Kingsley","doi":"10.2217/17469600.2.6.539","DOIUrl":null,"url":null,"abstract":"Aim: To investigate the association between self-reported physical function (as a surrogate for physical activity) and diabetes mellitus (DM) and insulin resistance (IR) among HIV-positive and -negative men.Method: A total of 384 HIV-negative and 274 HIV-positive men from the Pitt Men's Study contributed data. DM was defined by fasting serum glucose levels. IR was calculated using the homeostasis model assessment. The Physical Functioning 10 Scale from the Short Form-36 Health Survey measured physical function. Multivariate logistic regression assessed the independent association between physical function and DM and IR.Results: Physical function, older age and Black race were associated with DM in multivariate analyses. Physical function/HIV interaction, older age, higher body mass index, HIV infection and Black race were associated with IR in multivariate analyses.Conclusion: Self-reported low physical function is associated with DM and IR in HIV-negative and -positive men.","PeriodicalId":88489,"journal":{"name":"Future HIV therapy","volume":"2 6","pages":"539-549"},"PeriodicalIF":0.0000,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/17469600.2.6.539","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future HIV therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/17469600.2.6.539","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 4

Abstract

Aim: To investigate the association between self-reported physical function (as a surrogate for physical activity) and diabetes mellitus (DM) and insulin resistance (IR) among HIV-positive and -negative men.

Method: A total of 384 HIV-negative and 274 HIV-positive men from the Pitt Men's Study contributed data. DM was defined by fasting serum glucose levels. IR was calculated using the homeostasis model assessment. The Physical Functioning 10 Scale from the Short Form-36 Health Survey measured physical function. Multivariate logistic regression assessed the independent association between physical function and DM and IR.

Results: Physical function, older age and Black race were associated with DM in multivariate analyses. Physical function/HIV interaction, older age, higher body mass index, HIV infection and Black race were associated with IR in multivariate analyses.

Conclusion: Self-reported low physical function is associated with DM and IR in HIV-negative and -positive men.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

在hiv阳性和hiv阴性的男性中，自我报告的低身体机能与糖尿病和胰岛素抵抗有关。

目的:探讨hiv阳性和阴性男性自我报告的身体功能(替代体力活动)与糖尿病(DM)和胰岛素抵抗(IR)的关系。方法:来自皮特男性研究的384名hiv阴性和274名hiv阳性男性提供数据。糖尿病的定义是空腹血糖水平。利用稳态模型评估计算IR。来自健康调查简表-36的身体功能量表测量了身体功能。多变量logistic回归评估身体功能与糖尿病和IR之间的独立关联。结果:在多因素分析中，身体机能、年龄和黑人种族与糖尿病相关。在多变量分析中，身体功能/HIV相互作用、年龄较大、较高的体重指数、HIV感染和黑人种族与IR相关。结论:在hiv阴性和阳性男性中，自我报告的低身体功能与糖尿病和IR有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Future HIV therapy

自引率

0.00%

发文量