Should HRT be duration limited?

Joan Pitkin
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Abstract

Hormone Replacement Therapy (HRT) has received consistently bad press, despite re-analysis of previous data new studies and supporting Consensus Statements from leading national and international societies. Many women have been convinced by women's journals and the media not to even consider HRT as an option and, General Practitioners, still limit duration to 5 years or, will, arbitrarily, discontinue prescriptions in the early 50s. This article seeks to make sense of our current position. Previous and new evidence on the safety of HRT is reviewed. New data on the long-term consequences of non-treatment of women with Premature Ovarian Insufficiency (POI) is presented and the dichotomy of the older female workforce is explored. From this, a logical plan of management emerges.

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激素替代疗法应该有持续时间限制吗?
激素替代疗法(HRT)一直受到负面报道,尽管对以前的数据进行了重新分析,新的研究和支持主要国家和国际社会的共识声明。许多妇女被妇女杂志和媒体说服,甚至不考虑将激素替代疗法作为一种选择,而全科医生仍然将持续时间限制在5年以内,或者在50年代初武断地停止处方。这篇文章试图解释我们目前的处境。综述了激素替代疗法安全性的既往和新证据。关于未治疗卵巢功能不全(POI)妇女的长期后果的新数据被提出,并对老年女性劳动力的二分法进行了探讨。由此,一个合乎逻辑的管理计划出现了。
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