Premature coronary heart disease and traditional risk factors-can we do better?

IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS International Cardiovascular Research Journal Pub Date : 2013-06-01
Roxana Sadeghi, Nadia Adnani, Azam Erfanifar, Latif Gachkar, Zohre Maghsoomi
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引用次数: 0

Abstract

Background: Traditional cardiovascular risk factors are strong predictors of an increased likelihood for premature CHD. Considering the benefits of risk factors᾿ management, it is imperative to find and treat them before looking for more unknown and weak risk factors.

Objectives: Limited information is available about the demographic and historical characteristics of the patients with premature Coronary Heart Disease (CHD) in IR Iran. The main objective of this study was to determine the prevalence of the traditional risk factors in these patients. Also, the researchers hypothesized that there are insufficient risk assessment and preventive intervention methods for the asymptomatic adult population.

Methods: This study was conducted on 125 patients with premature CHD (age<50 years) who were admitted in two academic hospitals with acute coronary syndromes. The patients were accepted since they had a definite CHD on the basis of acute myocardial infarction (elevated cardiac enzymes) or documented CAD in coronary angiography.

Results: The mean age of the study population was 42.50±5.65 (26 to 49 years). Among the patients,92 (73.6%) were male, 113 (90.4%) were married, 58 (46.4%) were smokers,19 (15.2%) were opium users, 97 (77.6%) had dyslipidemia, 44 (35.2%) had hypertension, and 33 (26.4%) had diabetes mellitus. In addition, family history was presented in 54 patients (43.2%). Among the study population, 120 patients (96%) had at least one of the traditional risk factors, including dyslipidemia, hypertension, diabetes mellitus, cigarette smoking, and family history of CHD. However, none of the dyslipidemic patients had controlled total cholesterol, LDL, HDL, and triglyceride. Also, none of the diabetic patients had hemoglobin A1C<7%. Among the 44 hypertensive patients, blood pressure of 15 ones (34%) was within the normal range. Besides, only 3 patients (2.4%) had regular physical activity (at least 30 minutes, three times a week).

Conclusions: Premature Coronary Heart Disease is a public health problem. However, there is lack of effective and intensive treatments of well-defined traditional risk factors and prevention methods for the majority of the patients experiencing premature CHD. In sum, there is still plenty of room for improvement of risk management in IR Iran.

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早发冠心病和传统危险因素——我们能做得更好吗?
背景:传统的心血管危险因素是早期冠心病可能性增加的有力预测因素。考虑到风险因素管理的效益,在寻找更多未知的和微弱的风险因素之前,必须先发现并处理它们。目的:关于伊朗早期冠心病(CHD)患者的人口学和历史特征的信息有限。本研究的主要目的是确定这些患者中传统危险因素的患病率。此外,研究人员还假设没有足够的风险评估和预防干预方法用于无症状的成人人群。方法:对125例早发型冠心病患者(年龄)进行研究。结果:研究人群的平均年龄为42.50±5.65(26 ~ 49岁)。其中男性92例(73.6%),已婚113例(90.4%),吸烟58例(46.4%),吸食鸦片19例(15.2%),血脂异常97例(77.6%),高血压44例(35.2%),糖尿病33例(26.4%)。此外,54例(43.2%)患者有家族史。在研究人群中,120例患者(96%)至少有一种传统危险因素,包括血脂异常、高血压、糖尿病、吸烟和冠心病家族史。然而,没有一个血脂异常患者的总胆固醇、低密度脂蛋白、高密度脂蛋白和甘油三酯得到控制。结论:早发性冠心病是一个公共卫生问题。然而,对于大多数早期冠心病患者,缺乏明确的传统危险因素和预防方法的有效和强化治疗。总之,伊朗的风险管理仍有很大的改进空间。
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来源期刊
International Cardiovascular Research Journal
International Cardiovascular Research Journal CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
0.40
自引率
50.00%
发文量
0
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