Cefdinir.

Q1 Pharmacology, Toxicology and Pharmaceutics Profiles of drug substances, excipients, and related methodology Pub Date : 2014-01-01 DOI:10.1016/B978-0-12-800173-8.00002-7

Abdullah A Al-Badr, Fahad A Alasseiri

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引用次数: 3

Abstract

Cefdinir is a third-generation oral cephalosporin antibiotic. Nomenclature, formulae, elemental analysis, and appearance of the drug are mentioned. The uses and applications and the several methods described for its preparation of the drug are outlined. The profile contains the physical characteristics including: pKa value, solubility, X-ray powder diffraction, melting point, and differential scanning calorimetry. The ultraviolet spectrum, vibrational spectrum, nuclear magnetic resonance ((1)H and (13)C NMR) spectra and the mass spectrum and fragmentation patterns of cefdinir together with the corresponding figures and/or tables are all produced. This profile includes the monographs of the Japanese pharmacopeia and the United States pharmacopeia. The several reported analytical methods that had been reported of the analysis of cefdinir include: spectrophotometric, polarographic, voltammetric, and chromatographic methods. The pharmacokinetics and stability of the drug are also provided. About 80 references are listed at end of this comprehensive profile.

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头孢地尼。

头孢地尼是第三代口服头孢菌素类抗生素。命名法，配方，元素分析和药物的外观被提及。概述了该药物的用途和应用以及所述的几种制备方法。该剖面包含物理特征，包括:pKa值、溶解度、x射线粉末衍射、熔点和差示扫描量热。给出了头孢地尼的紫外光谱、振动谱、核磁共振((1)H和(13)C NMR)谱、质谱和破碎谱，并给出了相应的图表。该概况包括日本药典和美国药典的专著。已经报道的几种分析头孢地尼的方法包括:分光光度法、极谱法、伏安法和色谱法。还提供了药物的药代动力学和稳定性。在这篇综合简介的末尾列出了大约80篇参考文献。

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