[Usefulness of the initial medical examination on matters relating to persons suspected of driving under the influence of amphetamine and its analogs or delta9-tetrahydrocannabinol based on the materials the Department of Forensic Medicine, Pomeranian Medical University in Szczecin].

Stanisław Wolski, Ewa Lewandowska, Małgorzata Kurzejamska-Parafiniuk
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Abstract

Introduction: Polish law forbids persons to drive under the influence of intoxicating substances, and those after the use of substances producing effects similar to alcohol. Therefore, there is a need to give an opinion based on a blood test, to establish whether or not the person from whom the blood was taken was under the influence of an intoxicating substance or after use of the drug while driving. Some authors reported that the final opinion should take into account chemical and toxicology test results identifying the parent compound and/or the metabolite only, but also the sampling time of the material to be analyzed in relation to the driving time, the result of the medical examination conducted prior to the collection of material for analysis, and the results of screening tests executed at the scene. Circumstances relating to the event, the findings and observations of third parties, and the testimony of the suspect are also relevant. The aim of this study was to evaluate the results of the medical examination in the evaluation of cases concerning driving by persons who were potentially under the influence of amphetamine and its analogs, or delta9-tetrahydrocannabinol, (delta9-THC) and conformity assessment of these results with the results of blood tests. An additional aim was to determine the factors considered by doctors when making their evaluation of patient's condition.

Material and methods: The study group consisted of 350 persons suspected of driving while under the influence of amphetamine and its analogs, and/or delta9-THC, from whom blood samples were taken to test amphetamine content or its analogues and/or delta9-tetrahydrocannabinol. Blood tests were carried out according to the existing procedure developed by the department. Blood samples were initially analyzed with immunochemical methods. Positive preliminary results were verified by gas chromatography-mass spectrometry. Statistical analysis was conducted with independent tests for multi-way tables, i.e. the Pearson chi2 test and the 2 x 2 tables Yates' correction was used for the low numbers. Comparison of mean concentrations of amphetamine and delta9-THC in the blood was performed using the U Mann-Whitney test.

Results: The analysis revealed a significant correlation between the symptoms and the results of the chemical-toxicological blood tests for mood only. There was no significant correlation between the results of toxicological and physical elements contained in the protocol of blood collection as the skin's appearance, speech, heart rate, pupil, pupil reaction to light, walking, lifting objects off the ground, the Romberg test, the finger-to-nose test and orientation in the space time environment. In the analysis of the relationship between the medical assessment and physical elements significant relationships with the assessment of mood, pupils, pupil reaction to light and gait were found. A significant correlation between the prevalence of symptoms in terms of any/none and medical evaluation was found.

Conclusions: 1. Preliminary medical examination based on the blood sampling protocol has no practical importance for determining whether a person is tested under the influence of amphetamines or its analogues and/or delta9-THC. 2. The confirmation of the state "under the influence of narcotics or psychotropics" should only be based on blood test results. 3. Doctors, when completing the blood collection report, are often guided by factors other than the test results when making assessment. 4. The low utility of the medical examination is affected by lack of standardization of test items. Doctors often find symptoms in a subjective manner.

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[根据什切青波美拉尼亚医科大学法医学系的材料,对涉嫌在安非他明及其类似物或德尔塔9-四氢大麻酚影响下驾车的人进行初步医学检查的有用性]。
导言:波兰法律禁止人们在中毒物质的影响下驾驶,以及在使用类似酒精的物质后驾驶。因此,有必要根据血液检查提出意见,以确定被抽血的人是否受到麻醉物质的影响或在驾驶时使用该药物后。一些提交人报告说,最后意见应考虑到仅确定母体化合物和/或代谢物的化学和毒理学试验结果,但也应考虑到待分析材料的取样时间与驾驶时间的关系、收集材料进行分析之前进行的体检结果以及在现场进行的筛选试验结果。与事件有关的情况、第三方的调查结果和意见以及嫌疑人的证词也具有相关性。本研究的目的是评估在评估可能受安非他明及其类似物或德尔塔9-四氢大麻酚(德尔塔9-四氢大麻酚)影响的人驾驶案件中的医学检查结果,并评估这些结果与血液检查结果的一致性。另一个目的是确定医生在评估病人病情时所考虑的因素。材料和方法:研究组由350名涉嫌在安非他明及其类似物和/或德尔塔9-四氢大麻酚影响下驾驶的人组成,从他们身上采集血液样本以检测安非他明或其类似物和/或德尔塔9-四氢大麻酚的含量。血液检查是根据该部门制定的现有程序进行的。血液样本首先用免疫化学方法进行分析。通过气相色谱-质谱联用验证了阳性初步结果。统计分析采用多路表独立检验,即Pearson chi2检验,低数采用2 × 2表Yates校正。采用U - Mann-Whitney试验比较血液中苯丙胺和δ 9-四氢大麻酚的平均浓度。结果:分析揭示了症状与仅针对情绪的化学毒理学血液测试结果之间的显著相关性。血液采集方案中包含的毒理学和物理元素的结果与皮肤外观、言语、心率、瞳孔、瞳孔对光的反应、行走、举离地面物体、Romberg测试、手指到鼻子测试和时空环境中的方向没有显著的相关性。在分析医学评价与生理因素的关系时,发现情绪、瞳孔、瞳孔对光反应和步态评价与医学评价有显著关系。发现有/无症状的患病率与医学评估之间存在显著相关性。结论:1。基于血液取样方案的初步医学检查对于确定一个人是否在安非他明或其类似物和/或δ 9-四氢大麻酚的影响下进行测试没有实际重要性。2. 确认“受麻醉品或精神药物影响”的状态只能基于血液测试结果。3.医生在完成采血报告时,往往以检测结果以外的因素为指导进行评估。4. 体检项目缺乏标准化,影响了体检的低利用率。医生常常以主观的方式发现症状。
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