Renal solitary fibrous tumour: A rare pathological entity.

Biao Dong, Jianjian Zhang, Gang Wang, Xiuyu Zhai, Yaowen Fu, Honglan Zhou, Yuantao Wang
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引用次数: 2

Abstract

A solitary fibrous tumour (SFT) is a rare mesenchymal cell neoplasm that can develop at any site. SFT of the kidney is extremely rare. Recently, we had a case of solitary fibrous tumour involving the left kidney in a 71-year-old female patient. The SFT was incidentally found by imaging modalities at the time of a physical workup. Computed tomography and retrograde pyelography showed a 4 × 3.5 × 4-cm nodular mass in the middle poles of the left kidney adjacent to the renal pelvis. A laparoscopic radical resection of the left kidney was performed. The tumour was well-circumscribed and composed of a mixture of spindle cells; microscopically, we found dense collagenous bands. Immunohistochemical studies showed strong reactions with CD34, bcl-2 and CD99. A nuclear positivity with Ki-67 was observed in less than 1% of cells. The tumour was negative for desmin, SMA and CD117. Histopathological and immunohistochemical studies confirmed the diagnosis of a solitary fibrous tumour.

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肾孤立性纤维瘤:一种罕见的病理实体。
单发纤维性肿瘤(SFT)是一种罕见的间充质细胞肿瘤,可在任何部位发生。肾脏的SFT极为罕见。最近,我们有一个病例孤立的纤维性肿瘤累及左肾在一个71岁的女性患者。SFT是在物理检查时偶然通过成像方式发现的。计算机断层扫描和肾盂造影显示左肾中极有一个4 × 3.5 × 4厘米的结节状肿块,靠近肾盂。行腹腔镜左肾根治性切除术。肿瘤边界分明,由梭形细胞混合组成;显微镜下,我们发现致密的胶原带。免疫组化研究显示与CD34、bcl-2和CD99有强烈反应。Ki-67核阳性的细胞不到1%。desmin、SMA和CD117均阴性。组织病理学和免疫组织化学研究证实了孤立性纤维性肿瘤的诊断。
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