[Comparative investigation of rheological characteristics of the original drug Triderm and its generics in the form of cream].

Q4 Medicine Antibiotiki i Khimioterapiya Pub Date : 2014-01-01
E I Molokhova, Iu V Sorokina
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引用次数: 0

Abstract

Rheological properties of mild pharmaceutical formulations (creams) with glucocorticosteroids, such as Triderm (Belgium), Akriderm GK (Russia) and Kanizon plus (India) were studied. The study revealed differences in the structural-strength properties of the medicines (viscosity, critical shear stress). The necessity of rheological investigations during development of generic medicines was shown.

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【原料药Triderm与仿制药乳膏形式流变学特性的比较研究】。
研究了含糖皮质激素的温和药物制剂(乳膏)的流变学性质,如Triderm(比利时)、Akriderm GK(俄罗斯)和Kanizon plus(印度)。该研究揭示了药物的结构强度特性(粘度、临界剪切应力)的差异。指出了在仿制药开发过程中进行流变学研究的必要性。
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来源期刊
Antibiotiki i Khimioterapiya
Antibiotiki i Khimioterapiya Medicine-Infectious Diseases
CiteScore
0.80
自引率
0.00%
发文量
46
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