A Virtual Patient Simulator Based on Human Connectome and 7 T MRI for Deep Brain Stimulation.

Giorgio Bonmassar, Leonardo M Angelone, Nikos Makris
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Abstract

This paper presents a virtual model of patients with Deep Brain Stimulation implants. The model is based on Human Connectome and 7 Tesla Magnetic Resonance Imaging (MRI) data. We envision that the proposed virtual patient simulator will enable radio frequency power dosimetry on patients with deep brain stimulation implants undergoing MRI. Results from the proposed virtual patient study may facilitate the use of clinical MRI instead of computed tomography scans. The virtual patient will be flexible and morphable to relate to patient-specific neurological and psychiatric conditions such as Obsessive Compulsive Disorder, which benefit from deep brain stimulation.

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基于人体连接组和7t MRI的深部脑刺激虚拟患者模拟器。
本文提出了一个深部脑刺激植入物患者的虚拟模型。该模型基于人类连接组和7个特斯拉磁共振成像(MRI)数据。我们设想提出的虚拟患者模拟器将使接受MRI的深部脑刺激植入物患者的射频功率剂量测定成为可能。拟议的虚拟患者研究的结果可能有助于使用临床MRI代替计算机断层扫描。虚拟病人将是灵活的和可变形的,与病人特定的神经和精神疾病有关,如强迫症,这得益于深部脑刺激。
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A Virtual Patient Simulator Based on Human Connectome and 7 T MRI for Deep Brain Stimulation. Potential Antibacterial Targets in Bacterial Central Metabolism.
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