[Response to treatment of patients abusing the "dappou drug" who participated in a group relapse prevention program: a comparison with patients abusing methamphetamine].

Emi Hikitsuchi, Toshihiko Matsumoto, Kiyoshi Wada, Yuko Tanibuchi, Ayumi Takano, Fumi Imamura, Hiraku Kawachi, Asako Wakabayashi, Takashi Kato
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Abstract

In this study, we compared the efficacy of a group relapse prevention program using the cognitive behavioral therapy-based workbook, Serigaya Methamphetamine Relapse Prevention Program (SMARPP), between patients abusing the so-called "dappou drugs" (designer drug in Japan, and those abusing methamphetamine (MAP). Both groups participated in the SMARPP at the Center Hospital, National Center of Neurology and Psychiatry. Results showed that, no significant differences were found in the rates of participation in the program or self-reported frequency of drug or alcohol use between the patients abusing "dappou drugs" or MAP. However, patients using "dappou drugs" reported no significant increase in their confidence in their ability to resist the temptation to use drugs on the self- report drug abuse scales after the SMARPP intervention, while patients abusing MAP reported a significant positive difference in their ability to resist temptation. In addition, insight into substance abuse problems and motivation to participate in further treatment slightly declined in those using "dappou drugs," while there was a significant increase reported by the patients using MAP. These results suggested that the SMARPP might not be as effective for patients abusing "dappou drugs" as for those abusing MAP. The development of a relapse prevention program specifically designed for patients abusing "dappou drugs" is required.

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[参与团体预防复发项目的滥用“dappou药物”患者的治疗效果:与滥用甲基苯丙胺患者的比较]。
在这项研究中,我们比较了使用基于认知行为治疗的工作手册“Serigaya甲基苯丙胺复发预防计划”(SMARPP)的群体复发预防计划在滥用所谓的“dappou药物”(日本的设计药物)和滥用甲基苯丙胺(MAP)的患者之间的疗效。两组都参加了国家神经病学和精神病学中心医院的SMARPP。结果表明,在滥用“dappou药物”或MAP的患者之间,参与该计划的比率或自我报告的药物或酒精使用频率没有显着差异。然而,在SMARPP干预后,使用“dappou药物”的患者在自我报告药物滥用量表上对抵制药物诱惑能力的信心没有显著增加,而滥用MAP的患者在抵制诱惑能力上有显著的正差异。此外,使用“dappou药物”的患者对药物滥用问题的洞察力和参与进一步治疗的动机略有下降,而使用MAP的患者则有显着增加。这些结果表明,SMARPP对滥用“dappou药物”的患者可能不如滥用MAP的患者有效。有必要为滥用“dappou药物”的患者制定一个预防复发的方案。
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Reward signals downstream of dopamine D1 receptors. The potential of e-Health for treatment and prevention for drug dependence process of development and revision of web-based relapse prevention program "e-SMARPP". Dependence/addiction/use disorder from a therapeutic perspective -A preliminary study of preference for terms describing the condition. Alteration of Breath Hydrogen and Methane in Ethanol-Fed Rats. Effectiveness evaluation of Serigaya Methamphetamine Relapse Prevention Program in drug addiction rehabilitation center.
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