N V Kostiuk, M B Belyakova, D V Leshchenko, V V Zhigulina, M V Miniaev
{"title":"Synthetic melatoninergic ligands: achievements and prospects.","authors":"N V Kostiuk, M B Belyakova, D V Leshchenko, V V Zhigulina, M V Miniaev","doi":"10.1155/2014/843478","DOIUrl":null,"url":null,"abstract":"<p><p>Pineal hormone melatonin is widely used in the treatment of disorders of circadian rhythms. The presence of melatonin receptors in various animal tissues motivates the use of this hormone in some other diseases. For this reason, in recent years investigators continued the search for synthetic analogues of melatonin which are metabolically stable and selective to receptors. This review includes recent information about the most famous melatonin analogues, their structure, properties, and physiological features of the interaction with melatonin receptors. </p>","PeriodicalId":90189,"journal":{"name":"ISRN biochemistry","volume":"2014 ","pages":"843478"},"PeriodicalIF":0.0000,"publicationDate":"2014-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/843478","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ISRN biochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2014/843478","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2014/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
Pineal hormone melatonin is widely used in the treatment of disorders of circadian rhythms. The presence of melatonin receptors in various animal tissues motivates the use of this hormone in some other diseases. For this reason, in recent years investigators continued the search for synthetic analogues of melatonin which are metabolically stable and selective to receptors. This review includes recent information about the most famous melatonin analogues, their structure, properties, and physiological features of the interaction with melatonin receptors.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
