Long-Term Function, Pain and Medication Use Outcomes of Radiofrequency Ablation for Lumbar Facet Syndrome.

Zachary L McCormick, Benjamin Marshall, Jeremy Walker, Robert McCarthy, David R Walega
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引用次数: 59

Abstract

Objective: Radiofrequency ablation (RFA) of the medial branch nerves for facet-mediated low back pain demonstrates clinical benefit for 6-12 months and possibly up to 2 years. This study investigated function, pain, and medication use outcomes of RFA for lumbar facet syndrome in a cohort with long-term follow-up.

Methods: Individuals evaluated in a tertiary academic pain practice between January, 2007-December, 2013, 18-60 years of age, with a clinical and radiologic diagnosis of lumbar facet syndrome, who underwent ≥1set of diagnostic medial branch blocks with resultant >75% pain relief and subsequent RFA were included. Outcomes measured were the proportion of individuals who reported ≥50% improvement in function, ≥50% improvement in pain; change in median NRS pain score, daily morphine equivalent consumption (DME), Medication Quantification Scale III (MSQ III) score and procedure complications.

Results: Sixty-two consecutive individuals with a median age and 25%-75% interquartile range (IQR) of 34 years (35, 52) met inclusion criteria. Seven individuals were lost to follow-up. Duration of pain was <2 years in 42%, 2-5 years in 40%, >5 years in 18% of individuals. Median duration of follow-up was 39 months (16, 60). Function and pain improved by ≥50% in 58% (CI 45%, 71%) and 53% (CI 40%, 66%) of individuals, respectively. The median reduction in MQS III score was 3.4 points (0, 8.8). No complications occurred in this cohort.

Conclusions: This study demonstrates a durable treatment effect of RFA for lumbar facet syndrome at long-term follow-up, as measured by improvement in function, pain, and analgesic use.

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射频消融术治疗腰椎关节突综合征的长期功能、疼痛和用药结果。
目的:射频消融(RFA)内侧支神经治疗面介导的腰痛显示了6-12个月甚至可能长达2年的临床益处。本研究在一个长期随访的队列中调查了RFA治疗腰椎关节突综合征的功能、疼痛和药物使用结果。方法:纳入2007年1月至2013年12月在三级学术疼痛实践中评估的个体,年龄18-60岁,临床和放射学诊断为腰椎关节突综合征,接受≥1组诊断性内侧支阻滞治疗,疼痛缓解>75%,随后进行RFA。测量的结果是报告功能改善≥50%、疼痛改善≥50%的个体比例;NRS疼痛评分中位数、每日吗啡当量消耗量(DME)、用药量化量表III (MSQ III)评分和手术并发症的变化。结果:连续62例患者,年龄中位数为34岁,25%-75%四分位数间距(IQR)为35,52岁,符合纳入标准。7人失去随访。18%的患者疼痛持续时间为5年。中位随访时间为39个月(16,60)。58% (CI 45%, 71%)和53% (CI 40%, 66%)患者的功能和疼痛改善≥50%。MQS III评分中位下降3.4分(0,8.8分)。该队列中未发生并发症。结论:在长期随访中,该研究证明了RFA治疗腰椎关节突综合征的持久疗效,通过改善功能、疼痛和止痛药的使用来衡量。
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