Synchronized Laparoscopic Bilateral Adrenalectomy for Pheochromocytoma in Multiple Endocrine Neoplasia Syndrome: A Case Report.

IF 1.9 Q3 ONCOLOGY Journal of Kidney Cancer and VHL Pub Date : 2022-09-02 eCollection Date: 2022-01-01 DOI:10.15586/jkcvhl.v9i3.239
Ali Eslahi, Shahryar Zeighami, Faisal Ahmed, Seyed Hossein Hosseini, Bahareh Ebrahimi, Mohammad Hossein Anbardar
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Abstract

Pheochromocytomas are tumors producing catecholamines that arise from chromaffin cells in the adrenal medulla. They are usually benign in multiple endocrine neoplasia type 2 (MEN2) syndrome, but they tend to present bilaterally in 50-80% of the patients. Few researchers have reported success with simultaneous laparoscopic bilateral adrenalectomy. Hence, we report a 48-year-old woman who presented with a panic attack, headache, and abdominal discomfort that had started 10 years ago. The computed tomography (CT) scan showed a large bilateral cystic lesion in both adrenal glands in favor of pheochromocytomas (30 × 22 mm and 18 × 15 mm on the right side and 40 × 33 mm and 35 × 28 mm on the left side). The patient underwent bilateral laparoscopic adrenalectomy without intraoperative or postoperative complications. The total blood loss was 50 cc, and the operative time was 4 h. The histopathology of the specimen revealed pheochromocytomas of adrenal masses. In conclusion, our case demonstrates that synchronized laparoscopic bilateral adrenalectomy can be a safe and feasible treatment option for pheochromocytomas in MEN2 patients.

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同步腹腔镜双侧肾上腺切除术治疗多发性内分泌瘤综合征嗜铬细胞瘤1例。
嗜铬细胞瘤是由肾上腺髓质的嗜铬细胞产生儿茶酚胺的肿瘤。在多发性内分泌瘤2型(MEN2)综合征中,它们通常是良性的,但在50-80%的患者中,它们往往表现为双侧。很少有研究者报道同时腹腔镜双侧肾上腺切除术的成功。因此,我们报告一位48岁的女性,她在10年前开始出现恐慌发作,头痛和腹部不适。计算机断层扫描(CT)显示双侧肾上腺大囊性病变,支持嗜铬细胞瘤(右侧30 × 22 mm和18 × 15 mm,左侧40 × 33 mm和35 × 28 mm)患者行双侧腹腔镜肾上腺切除术,无术中或术后并发症。总失血量50cc,手术时间4h。标本组织病理学显示肾上腺嗜铬细胞瘤。总之,我们的病例表明同步腹腔镜双侧肾上腺切除术是MEN2患者嗜铬细胞瘤的一种安全可行的治疗选择。
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审稿时长
4 weeks
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