Autophagy in cell fate decisions: knowledge gained from Drosophila.
IF 1.7 3区 生物学Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGYGenomePub Date : 2022-12-01Epub Date: 2022-10-14DOI:10.1139/gen-2022-0069
Camille Lacarrière-Keïta, Sonya Nassari, Steve Jean
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引用次数: 0
Abstract
Autophagy is an important process that maintains adult tissue homeostasis and functions by protecting cells in autonomous and non-cell-autonomous ways. By degrading toxic components or proteins involved in cell signaling pathways, autophagy preserves the balance among stem cells, progenitors, and differentiated cells in various tissues. In this minireview, we discuss recent studies performed in Drosophila that highlight new roles of autophagy in adult cell fate decisions, including quiescence, proliferation, differentiation, and death.
期刊介绍：
Genome is a monthly journal, established in 1959, that publishes original research articles, reviews, mini-reviews, current opinions, and commentaries. Areas of interest include general genetics and genomics, cytogenetics, molecular and evolutionary genetics, developmental genetics, population genetics, phylogenomics, molecular identification, as well as emerging areas such as ecological, comparative, and functional genomics.
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