{"title":"A novel host–guest recognition electrochemiluminescence system for phenylalanine detection based on Ir@ZnO nanocomposites and cucurbit[8]uril","authors":"Yuhua Luo, Yahui Zhang, Qidong Cao, Yongping Dong","doi":"10.1016/j.jelechem.2023.117670","DOIUrl":null,"url":null,"abstract":"<div><p>Iridium complexes have been considered as potential promising electrochemiluminescent (ECL) reagents in recent years. However, the instability of ECL signal and easy leaching from the electrode severely limit their applications. In this work, iridium complex doped zinc oxide (ZnO) nanocomposites (Ir@ZnO) were synthesized, which could not only increase the loading amount of iridium complex, but also improve the stability of ECL signal. A sensitive ECL sensor for the detection of phenylalanie (Phe) was proposed via the host–guest recognition of cucurbit[8]uril (Q[8]) and Phe with Ir@ZnO nanocomposites as a signal probe. Q[8] was combined with Ir@ZnO nanocomposites via coordinate bond between carbonyl group of Q[8] and Ir and Zn atoms, which could quench the ECL intensity due to the accommodating ability of Q[8] for dissolved oxygen. In the presence of Phe, Q[8] could be released from the electrode surface through the strong host–guest interaction, and the ECL intensity was restored. The ECL system performed high sensitivity and low detection limit, indicating that the proposed ECL strategy was suitable for the detection of amino acids. Moreover, this work provided a new avenue for the application of water insoluble Ir complexes in ECL sensing field.</p></div>","PeriodicalId":50545,"journal":{"name":"Journal of Electroanalytical Chemistry","volume":"944 ","pages":"Article 117670"},"PeriodicalIF":4.5000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Electroanalytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1572665723005301","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Chemical Engineering","Score":null,"Total":0}
引用次数: 1
Abstract
Iridium complexes have been considered as potential promising electrochemiluminescent (ECL) reagents in recent years. However, the instability of ECL signal and easy leaching from the electrode severely limit their applications. In this work, iridium complex doped zinc oxide (ZnO) nanocomposites (Ir@ZnO) were synthesized, which could not only increase the loading amount of iridium complex, but also improve the stability of ECL signal. A sensitive ECL sensor for the detection of phenylalanie (Phe) was proposed via the host–guest recognition of cucurbit[8]uril (Q[8]) and Phe with Ir@ZnO nanocomposites as a signal probe. Q[8] was combined with Ir@ZnO nanocomposites via coordinate bond between carbonyl group of Q[8] and Ir and Zn atoms, which could quench the ECL intensity due to the accommodating ability of Q[8] for dissolved oxygen. In the presence of Phe, Q[8] could be released from the electrode surface through the strong host–guest interaction, and the ECL intensity was restored. The ECL system performed high sensitivity and low detection limit, indicating that the proposed ECL strategy was suitable for the detection of amino acids. Moreover, this work provided a new avenue for the application of water insoluble Ir complexes in ECL sensing field.
期刊介绍:
The Journal of Electroanalytical Chemistry is the foremost international journal devoted to the interdisciplinary subject of electrochemistry in all its aspects, theoretical as well as applied.
Electrochemistry is a wide ranging area that is in a state of continuous evolution. Rather than compiling a long list of topics covered by the Journal, the editors would like to draw particular attention to the key issues of novelty, topicality and quality. Papers should present new and interesting electrochemical science in a way that is accessible to the reader. The presentation and discussion should be at a level that is consistent with the international status of the Journal. Reports describing the application of well-established techniques to problems that are essentially technical will not be accepted. Similarly, papers that report observations but fail to provide adequate interpretation will be rejected by the Editors. Papers dealing with technical electrochemistry should be submitted to other specialist journals unless the authors can show that their work provides substantially new insights into electrochemical processes.