[Antimicrobial Activity of Fungi Strains of Trichoderma from Middle Siberia].

V S Sadykova, A V Kurakov, A E Kuvarina, E A Rogozhin
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Abstract

The antibiotic activity in 42 strains of 8 species of the Trichoderma genus (T. asperellum, T. viride, T. hamatum, T. koningii, T. atroviride, T. harzianum, T. Citrinoviride, and T. longibrachiatum) isolated from different Siberian ecotops was studied. It was shown that these species differ in the degree of their antibacterial and antifungal activity. The chosen strain, T. citrinoviride TV4-1, exhibited high activity and a wide range of actions against the opportunistic and pathogenic fungi of the Aspergillus and Candida albicans genus; bacteria, including methicillin-resistant Staphylococcus aureus; and cancer cells. According to mass and I R spectrometry data and the spectrum of biological action, peptaibols are probably the most active compounds in the strain culture extracts.

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[中西伯利亚木霉菌种的抑菌活性]。
研究了从西伯利亚不同生态顶分离的8种木霉属(asperellum、T. viride、T. hamatum、T. koningii、T. atroviride、T. harzianum、T. Citrinoviride、T. longibrachiatum) 42株菌株的抗菌活性。结果表明,这些物种的抗菌和抗真菌活性程度不同。所选菌株柠檬酸葡萄球菌(T. citrinoviride TV4-1)对曲霉属和白色念珠菌属的机会性真菌和致病性真菌表现出高活性和广泛的作用;细菌,包括耐甲氧西林金黄色葡萄球菌;还有癌细胞。根据质谱和红外光谱数据以及生物活性谱,肽类化合物可能是菌株培养提取物中最具活性的化合物。
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