[Creation and Study of Triterpenoid Nanoparticles and Amphiphilic meso-Arylporphyrins].

Bioorganicheskaia khimiia Pub Date : 2015-03-01
H Q Nguyen, K A Zhdanova, V S Uvarova, N A Bragina, A F Mironov, V V Chupin, V I Svets
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Abstract

This work is devoted to the study of nanoparticles based on amphiphilic meso-arylporphyrins and spherical amorphous nanoparticles (SANp), consisting of birch bark triterpenoids mixture. Nanoparticles were investigated by electron microscopy, dynamic light scattering, UV spectroscopy and fluorimetry. It was shown the efficiency of the inclusion of porphyrin sensitizer to the nanoparticles and the use of these nanoparticles as drug delivery system.

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[三萜纳米颗粒和两亲性中芳基卟啉的制备与研究]。
本文研究了两亲性中芳基卟啉纳米粒子和由桦树皮三萜混合物组成的球形非晶纳米粒子(SANp)。采用电子显微镜、动态光散射、紫外光谱和荧光法对纳米颗粒进行了研究。研究结果表明,卟啉增敏剂包被在纳米颗粒上的有效性,以及这些纳米颗粒作为给药系统的使用。
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