[THE COURSE OF TUBERCULOSIS AND ITS TREATMENT EFFICIENCY IN PATIENTS WITH LATE-STAGE HIV INFECTION].

Q4 Medicine Tuberculosis and Lung Diseases Pub Date : 2010-01-01
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Abstract

The course of tuberculosis and efficiency of combination antituberculous and antiretroviral therapy were analyzed in 30 patients with late-stage HIV infection. The acute progressive course of tuberculosis was found to reduce the role of prophylactic fluorographic examination in this category of patients. Various diagnostic mini-invasive surgical procedures proved to be of great informative value (91.7% sensitivity) in the diagnosis of atypical tuberculosis. During the intensive phase, combination antituberculous and antiviral therapy with its high adherence yielded good clinical results: the median CD4 lymphocyte increase was 65 cells/µl; the therapy was acknowledged to be effective in treating the tuberculous process in 76.7% of the patients; mortality was 6.7%.

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[晚期HIV感染患者结核病的病程及治疗效果]。
分析30例晚期HIV感染患者的结核病程及抗结核药物与抗逆转录病毒药物联合治疗的效果。发现结核病的急性进展过程降低了这类患者预防性x线检查的作用。各种微创手术诊断对非典型结核的诊断具有重要的信息价值(91.7%的敏感性)。在强化期,高依从性的抗结核和抗病毒联合治疗取得了良好的临床效果:CD4淋巴细胞中位数增加65个细胞/µl;76.7%的患者认为该药能有效治疗结核;死亡率为6.7%。
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来源期刊
Tuberculosis and Lung Diseases
Tuberculosis and Lung Diseases Medicine-Pulmonary and Respiratory Medicine
CiteScore
1.20
自引率
0.00%
发文量
88
审稿时长
8 weeks
期刊介绍: The Journal is aimed for professional development of researchers, doctors, teachers of medical universities and training institutions. The Journal focuses on the presentation of results of research, case studies, issues of differential diagnostics and treatment in the phthisiologist’s practice, national programs on tuberculosis control in the Russian Federation, WHO strategies, discussion of prevention issues to stop transmission of TB/HIVco-infection, and extrapulmonary tuberculosis.
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