Retrospective analysis of a VACM (vacuum-assisted closure and mesh-mediated fascial traction) treatment manual for temporary abdominal wall closure - results of 58 consecutive patients.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2016-07-28 eCollection Date: 2016-01-01 DOI:10.3205/iprs000098

Christian Beltzer, Alexander Eisenächer, Steffen Badendieck, Dietrich Doll, Markus Küper, Stefan Lenz, Björn Dirk Krapohl

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引用次数: 18

Abstract

Introduction: The optimal treatment concept for temporary abdominal closure (TAC) in critically ill visceral surgery patients with open abdomen (OA) continues to be unclear. The VACM (vacuum-assisted closure and mesh-mediated fascial traction) therapy seems to permit higher delayed primary fascial closure rates (FCR) than other TAC procedures.

Material and methods: Patients of our clinic (n=58) who were treated by application of a VAC/VACM treatment manual in the period from 2005 to 2008 were retrospectively analysed.

Results: The overall FCR of all patients was 48.3% (95% confidence interval: 34.95-61.78). An FCR of 61.3% was achieved in patients who had a vicryl mesh implanted at the fascial level (VACM therapy) in the course of treatment. Mortality among patients treated with VACM therapy was 45.2% (95% CI: 27.32-63.97).

Conclusions: The results of our own study confirm the results of previous studies which showed an acceptable FCR among non-trauma patients who were treated with VACM therapy. VACM therapy currently appears to be the treatment regime of choice for patients with OA requiring TAC.

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对58例连续患者的临时腹壁闭合的VACM(真空辅助闭合和网状筋膜牵引)治疗手册的回顾性分析。

导读:对于危重脏器手术合并开腹(OA)患者，暂时闭腹(TAC)的最佳治疗理念仍不明确。真空辅助闭合和网状筋膜牵引(VACM)治疗似乎比其他TAC方法允许更高的延迟原发性筋膜闭合率(FCR)。材料和方法:回顾性分析我院2005 - 2008年应用VAC/VACM治疗手册治疗的58例患者。结果:所有患者的总FCR为48.3%(95%可信区间:34.95 ~ 61.78)。在治疗过程中，在筋膜水平植入vicryl网状物(VACM治疗)的患者的FCR达到61.3%。接受VACM治疗的患者死亡率为45.2% (95% CI: 27.32-63.97)。结论:我们自己的研究结果证实了先前的研究结果，即在接受VACM治疗的非创伤患者中FCR是可接受的。VACM治疗目前似乎是OA患者需要TAC的治疗方案的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.