[Treatment for self-injurious behavior in mentally handicapped populations--a report from our practice].

Q4 Medicine No To Hattatsu Pub Date : 2016-03-01
Ikumi Kimura, Hiroya Nishida, Naoto Yamaguchi, Mika Nagase, Junko Ohinata, Naoko Ishikawa, Michiko Kita, Katsutoshi Nakatani, Akira Yoneyama, Eiji Kitazumi
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Abstract

Objective: Self-injurious behavior (SIB) is a common problem in individuals with intellectual disabilities, yet its clinical management remains to be established. We aimed to clarify the background factors and profiles of SIB in mentally and physically handicapped subjects and subsequently examined the efficacy of treatments attempted in our practice in order to achieve a better understanding of SIB and appro- priate interventions in these populations.

Methods: We surveyed 92 mentally handicapped subjects with SIB (including 25 females and 67 males, most of whom also had physical disabilities) as outpatients or inpatients of our institution using a retrospective questionnaire com- pleted by the corresponding doctors.

Results: Regarding psychobehavioral complications, impulsive mood swings (such as sudden rage) were more frequent than other behaviors. As to probable triggers of SIB, the patient's physical condition (17 cases) and noise or the temperature of the surrounding environment (38 cases) were identified. A total of 81 of 92 patients were given a prescription for SIB. Risperidone was the most commonly prescribed drug (75 cases), found to be effective in 38 (50.6%) cases, whereas phenothiazine antipsychotics were often more effective in patients with profound SIB. SSRIs (selective serotonin reuptake inhibitors) were applied in 20 cases, being effective in only five (25%) patients and discontinued in 11 (55%) patients due to the onset of several side effects, including overexcitement. As an additional agent for mood control, the antiepileptic topiramate was effective in 10 (76.9%) of 13 cases. Aside from medication, equipment for elbow extension was beneficial in some of the patients with profound SIB.

Conclusions: Pharmacological intervention is sometimes beneficial, albeit only partly. Clinicians must therefore also consider triggers and factors in the surrounding environment for the development of SIB in mentally handicapped individuals.

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[智障人群自我伤害行为的治疗——来自我们实践的一份报告]。
目的:自伤行为(SIB)是智力障碍患者普遍存在的问题,但其临床管理仍有待建立。我们的目的是澄清SIB在精神和身体残疾受试者中的背景因素和概况,并随后检查我们实践中尝试的治疗效果,以便更好地了解SIB并在这些人群中采取适当的干预措施。方法:采用由主治医师填写的回顾性调查问卷,对我院门诊和住院的92例智障SIB患者(其中女25例,男67例,多伴有肢体残疾)进行调查。结果:在心理行为并发症中,冲动性情绪波动(如暴怒)比其他行为更常见。对于SIB的可能诱因,确定患者的身体状况(17例)和周围环境的噪音或温度(38例)。92名患者中共有81名患者获得了SIB处方。利培酮是最常用的处方药(75例),其中38例(50.6%)有效,而吩噻嗪类抗精神病药物对重度SIB患者通常更有效。选择性血清素再摄取抑制剂(SSRIs)在20例患者中使用,只有5例(25%)患者有效,11例(55%)患者因出现包括过度兴奋在内的几种副作用而停用。作为情绪控制的辅助药物,抗癫痫药托吡酯在13例患者中有10例(76.9%)有效。除了药物治疗外,肘部伸展设备对一些重度SIB患者是有益的。结论:药物干预有时是有益的,尽管只是部分有益。因此,临床医生还必须考虑周围环境中引发智障个体SIB发展的因素。
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No To Hattatsu
No To Hattatsu Medicine-Pediatrics, Perinatology and Child Health
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