Hadi Khodabandehloo, Hamid Zahednasab, Asghar Ashrafi Hafez
{"title":"Nanocarriers Usage for Drug Delivery in Cancer Therapy.","authors":"Hadi Khodabandehloo, Hamid Zahednasab, Asghar Ashrafi Hafez","doi":"10.17795/ijcp-3966","DOIUrl":null,"url":null,"abstract":"<p><p>Conventional therapeutic agents have displayed significant shortcomings. For this reason, important achievements have effectively made in biotechnology for delivering the therapeutic agents to the site of action, and diminish side effects. Polymeric carriers, micelles, dendrimers, liposomes, solid lipid carriers, gold carriers, viral carriers, nanotubes and magnetic carriers incorporating cytotoxic therapeutics have developed. To improve biological distribution of therapeutic drugs, some modified carriers have designed in optimal size and modified surface area. Delivery of carriers to target cells could be done by passive and active targeting. </p>","PeriodicalId":73510,"journal":{"name":"Iranian journal of cancer prevention","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.17795/ijcp-3966","citationCount":"73","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian journal of cancer prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17795/ijcp-3966","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2016/4/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 73
Abstract
Conventional therapeutic agents have displayed significant shortcomings. For this reason, important achievements have effectively made in biotechnology for delivering the therapeutic agents to the site of action, and diminish side effects. Polymeric carriers, micelles, dendrimers, liposomes, solid lipid carriers, gold carriers, viral carriers, nanotubes and magnetic carriers incorporating cytotoxic therapeutics have developed. To improve biological distribution of therapeutic drugs, some modified carriers have designed in optimal size and modified surface area. Delivery of carriers to target cells could be done by passive and active targeting.