Mandibular Reconstruction in Ameloblastoma Using Allogeneic Cord Stem Cells and Alloplastic Graft Material - Case Report.

Q4 Biochemistry, Genetics and Molecular Biology Journal of Stem Cells Pub Date : 2016-01-01
K Manimaran, M Chandramohan, R Kannan, S Sankaranarayanan, V R Ravi, Rohini Sharma
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Abstract

Ameloblastoma is a histologically benign odontogenic tumour and has a tendency of locally aggressive behaviour. This is second most prevalent odontogenic tumour and most common in the molar-ramus-angle region and surgical resection is only treatment option. In this article, we propose an innovative approach to deal with these cases by using alloplastic graft with cord stem cells. Over 2.5 years follow-up, we could demonstrate bone regeneration using this technique with no recurrence. To the best of our knowledge, this is the first report of successful regeneration of part of ramus and body of mandible using allogeneic cord stem cells in cases of Ameloblastoma.

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用同种异体脐带干细胞和同种异体移植材料重建下颌成釉细胞瘤1例报告。
成釉细胞瘤是一种组织学上良性的牙源性肿瘤,具有局部侵袭性倾向。这是第二常见的牙源性肿瘤,最常见于磨牙支角区,手术切除是唯一的治疗选择。在本文中,我们提出了一种创新的方法来处理这些病例,即使用同种异体移植脐带干细胞。在超过2.5年的随访中,我们可以证明使用该技术的骨再生无复发。据我们所知,这是首例使用同种异体脐带干细胞成功再生成釉细胞瘤患者下颌骨部分分支和体的报道。
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来源期刊
Journal of Stem Cells
Journal of Stem Cells Medicine-Transplantation
CiteScore
0.10
自引率
0.00%
发文量
1
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