A Prospective Study of Infectious Mononucleosis in College Students.

International journal of psychiatry (Overland Park) Pub Date : 2017-01-01 Epub Date: 2017-01-20

Leonard A Jason, Ben Katz, Kristen Gleason, Stephanie McManimen, Madison Sunnquist, Taylor Thorpe

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Abstract

Background: The present study aims to prospectively investigate possible biological and psychological factors present in college students who will go on to develop chronic fatigue syndrome (CFS) following Infectious Mononucleosis (IM). Identification of risk factors predisposing patients towards developing CFS may help to understand the underlying mechanisms and ultimately prevent its occurrence. Our study is enrolling healthy college students over the age of 18. Enrollment began in March of 2013 and is ongoing.

Methods: Biological and psychological data are collected when students are well (Stage 1), when they develop IM (Stage 2), and approximately 6 months after IM diagnosis (Stage 3).

Results: Two case studies demonstrate the progression of student symptomology across all three stages.

Conclusion: The Case Studies presented illustrate the usefulness of a prospective research design that tracks healthy students, following their trajectory of IM illness to either a) full recovery or b) diagnosis with CFS.

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大学生传染性单核细胞增多症前瞻性研究

研究背景本研究旨在前瞻性地调查大学生在感染传染性单核细胞增多症（IM）后可能患上慢性疲劳综合征（CFS）的生理和心理因素。找出患者易患慢性疲劳综合征的危险因素有助于了解其潜在机制，并最终预防其发生。我们的研究正在招募 18 岁以上的健康大学生。研究方法：方法：收集学生健康时（第 1 阶段）、患上综合症时（第 2 阶段）以及综合症确诊后约 6 个月（第 3 阶段）的生物和心理数据：结果：两个案例研究显示了学生症状在所有三个阶段的进展情况：所介绍的案例研究说明了前瞻性研究设计的实用性，该设计可跟踪健康学生的 IM 疾病发展轨迹，直至 a) 完全康复或 b) 确诊为 CFS。

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