Solitary fibrous tumor occurring in the parotid gland: a case report.

Q2 Medicine BMC Clinical Pathology Pub Date : 2017-11-21 eCollection Date: 2017-01-01 DOI:10.1186/s12907-017-0062-z
Meryem Rais, Amine Kessab, Zahra Sayad, Sanae El Mourabit, Redallah Zrarqi, Salma Benazzou, Malik Boulaadas, Nadia Cherradi
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引用次数: 10

Abstract

Background: Solitary fibrous tumor is an uncommon spindle cell neoplasm of unknown origin. It has been reported in many anatomic sites, with a rare occurrence in the head and neck region. Solitary fibrous tumors of the parotid gland are exceptional; their clinical and radiologic features are non specific, often mimicking more common salivary gland tumors. Pathologic examination and immunohistochemistry are required to make the correct diagnosis. The prognosis is favorable, with most tumors being benign, and complete surgical resection is the treatment of choice.

Case presentation: We report the case of a 42-year-old man who presented with a painless mass involving the parotid gland. A parotidectomy was performed, and follow up was unremarkable. Gross examination showed a well circumscribed, firm tumor measuring 3,4 cm. Histologically, the tumor was composed of a spindle cell proliferation of variable cellularity, with staghorn vessels. A panel of immunohistochemical stains was performed, and confirmed the diagnosis of parotid gland solitary fibrous tumor.

Conclusion: In this report we aim to increase awareness of this rare entity among clinicians and pathologists, and to emphasize the role of immunohistochemistry in confirming the diagnosis.

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孤立性纤维性肿瘤发生于腮腺:1例报告。
背景:孤立性纤维性肿瘤是一种少见的来源不明的梭形细胞肿瘤。它已在许多解剖部位报道,罕见的发生在头颈部区域。孤立的腮腺纤维性肿瘤是例外;它们的临床和放射学特征是非特异性的,通常与更常见的唾液腺肿瘤相似。正确的诊断需要病理检查和免疫组织化学。预后良好,大多数肿瘤是良性的,完全手术切除是治疗的选择。病例介绍:我们报告的情况下,一个42岁的男子谁提出了一个无痛性肿块涉及腮腺。行腮腺切除术,随访无显著差异。大体检查显示一个界限清楚、结实的肿瘤,直径为3,4厘米。组织学上,肿瘤由可变细胞的梭形细胞增生组成,有鹿角状血管。经免疫组化染色证实为腮腺孤立性纤维性肿瘤。结论:在本报告中,我们旨在提高临床医生和病理学家对这种罕见实体的认识,并强调免疫组织化学在确诊中的作用。
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来源期刊
BMC Clinical Pathology
BMC Clinical Pathology Medicine-Pathology and Forensic Medicine
CiteScore
3.30
自引率
0.00%
发文量
0
期刊介绍: BMC Clinical Pathology is an open access journal publishing original peer-reviewed research articles in all aspects of histopathology, haematology, clinical biochemistry, and medical microbiology (including virology, parasitology, and infection control). BMC Clinical Pathology (ISSN 1472-6890) is indexed/tracked/covered by PubMed, CAS, EMBASE, Scopus and Google Scholar.
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