Conjunctival Flora of Human Immunodeficiency Virus Patients on Antiretroviral Treatment.

Ophthalmology and eye diseases Pub Date : 2017-08-03 eCollection Date: 2017-01-01 DOI:10.1177/1179172117724760
Kagmeni Giles, Yannick Bilong, Andin Viola Dohvoma, Steve Robert Ebana, Hortance Gonsu
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引用次数: 2

Abstract

Objectives: To determine the conjunctival flora of human immunodeficiency virus (HIV) patients on antiretroviral treatment (ART). Methodology: A total of 104 conjunctival swabs from 104 HIV patients on ART underwent microbiological evaluation to describe the flora. Result: There were 71 (68.26%) women and 33 (31.74%) men. The mean age was 42.9 ± 9.77 (range: 22-70) years. Negative cultures were found in 39 (37.50%) cases. Bacterial growth occurred in 65 (62.50%) cases. Coagulase-negative Staphylococcus was found in 59 eyes (90.76%), and coagulase-positive in 3 eyes (4.61%). There was a significant correlation between the duration of ART, the degrees of immunosuppression, and bacterial growth. Conclusions: Knowledge of the conjunctival flora in HIV patients may provide a better guideline in the choice of antibiotic for the management of ocular surface infections.

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抗逆转录病毒治疗的人类免疫缺陷病毒患者结膜菌群。
目的:了解接受抗逆转录病毒治疗(ART)的人类免疫缺陷病毒(HIV)患者结膜菌群。方法:对104名接受抗逆转录病毒治疗的HIV患者的104份结膜拭子进行微生物学评估以描述菌群。结果:女性71例(68.26%),男性33例(31.74%)。平均年龄42.9±9.77岁(22 ~ 70岁)。39例(37.50%)培养阴性。65例(62.50%)出现细菌生长。凝固酶阴性葡萄球菌59眼(90.76%),凝固酶阳性葡萄球菌3眼(4.61%)。抗逆转录病毒治疗持续时间、免疫抑制程度和细菌生长之间存在显著相关性。结论:了解HIV患者结膜菌群可为治疗眼表感染选择抗生素提供更好的指导。
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