Human immune system during sleep.

IF 1.4 Q4 IMMUNOLOGY American journal of clinical and experimental immunology Pub Date : 2017-12-20 eCollection Date: 2017-01-01
Nayyab Asif, Razia Iqbal, Chaudhry Fahad Nazir
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Abstract

A joint function of tissues, organs and cells for the protection of body develops immune system. The human immune response against various infections during sleep, its mechanism, neuroimmune interactions, immunoregulatory effect of sleep along with sleep deprivation and role of cytokines in sleep deprivation were addressed. It is revealed that human immune system and sleep both are associated and influenced by each other. Sleep deprivation makes a living body susceptible to many infectious agents. In the result, immune system of human body is altered by releasing immunomodulators in the response of infections as reported by various researchers. Basic reasons and mechanisms of most of the poor sleep networks and release of proinflammatory modulators are still uncertain. The current situation requires improved sleep habits to make immune system efficient for a healthy life.

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人体免疫系统在睡眠中的作用。
免疫系统是组织、器官和细胞的联合功能,用于保护身体发育。本文阐述了人体在睡眠过程中对各种感染的免疫反应及其机制、神经免疫相互作用、睡眠与睡眠剥夺的免疫调节作用以及细胞因子在睡眠剥夺中的作用。研究表明,人体免疫系统与睡眠是相互联系、相互影响的。睡眠不足使活人容易受到许多传染因子的影响。因此,许多研究人员报道,人体免疫系统在感染反应中通过释放免疫调节剂来改变免疫系统。大多数不良睡眠网络和促炎调节剂释放的基本原因和机制仍不确定。目前的情况需要改善睡眠习惯,使免疫系统高效,健康生活。
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