Establishing the Role of Stereotactic Ablative Body Radiotherapy in Early-Stage Breast Cancer.

IF 1.6 Q4 ONCOLOGY International Journal of Breast Cancer Pub Date : 2018-02-01 eCollection Date: 2018-01-01 DOI:10.1155/2018/2734820
Aisling Barry, Anthony Fyles
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引用次数: 0

Abstract

Stereotactic ablative body radiotherapy (SABR) has a role as definitive therapy in many tumor sites; however, its role in the treatment of breast cancer is less well explored. Currently, SABR has been investigated in the neoadjuvant and adjuvant setting with a number of ongoing feasibility studies. However, its use comes with a number of radiobiological and technical challenges that require further evaluation. We have learned much from other extracranial disease sites such as lung, brain, and spine, where definitive treatment with SABR has shown encouraging outcomes. In women with breast cancer, SABR may eliminate the need for invasive surgery, reducing healthcare costs and hospital stays and providing an additional curative option for early-stage disease. This poses the following question: is there a role for SABR as a definitive therapy in breast cancer?

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确定立体定向烧蚀体放疗在早期乳腺癌中的作用。
立体定向消融体放射治疗(SABR)可作为许多肿瘤部位的最终治疗方法,但其在乳腺癌治疗中的作用却鲜有人问津。目前,SABR 已被用于新辅助和辅助治疗,并正在进行多项可行性研究。然而,SABR 的使用也带来了一些放射生物学和技术上的挑战,需要进一步评估。我们从肺部、脑部和脊柱等其他颅外疾病部位学到了很多经验,在这些部位,SABR 的最终治疗效果令人鼓舞。对于罹患乳腺癌的妇女,SABR 可以消除对侵入性手术的需求,减少医疗费用和住院时间,并为早期疾病提供额外的治愈选择。这就提出了以下问题:SABR 是否可作为乳腺癌的最终疗法?
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来源期刊
CiteScore
3.40
自引率
0.00%
发文量
25
审稿时长
19 weeks
期刊介绍: International Journal of Breast Cancer is a peer-reviewed, Open Access journal that provides a forum for scientists, clinicians, and health care professionals working in breast cancer research and management. The journal publishes original research articles, review articles, and clinical studies related to molecular pathology, genomics, genetic predisposition, screening and diagnosis, disease markers, drug sensitivity and resistance, as well as novel therapies, with a specific focus on molecular targeted agents and immune therapies.
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