[The Role of FGF21 in Regulating Lipid and Glucose Metabolism].

生理科学进展 Pub Date : 2016-08-01
Wen-Qi Yang, Wen-Hua Ling
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引用次数: 0

Abstract

Fibroblast growth factor 21 (FGF21), a member of fibroblast growth factor superfamily has received extensive attention for its positive effect on metabolism. Many tissues are target of FGF21 action. The effect of FGF21 on improving lipid and glucose metabolism has been proved. It also suggests that FGF21 plays a conspicuous role in a state of prolonged fasting and starvation. This article will review the role of FGF21 in regulating lipid and glucose metabolism and discuss the involved cellular and molecular mechanisms.

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[FGF21在调节脂糖代谢中的作用]。
成纤维细胞生长因子21 (Fibroblast growth factor 21, FGF21)是成纤维细胞生长因子超家族的一员,因其对代谢的积极作用而受到广泛关注。许多组织都是FGF21作用的靶点。FGF21改善脂糖代谢的作用已被证实。这也表明FGF21在长时间禁食和饥饿状态中起着显著的作用。本文将综述FGF21在调节脂质和糖代谢中的作用,并讨论其细胞和分子机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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期刊介绍: Progress in Physiological Sciences is a bimonthly academic journal co-sponsored by Chinese Association for Science and Technology, Chinese Physiological Society and Peking University. It was founded in March 1957. China Core Journal of Science and Technology, China Core Journal of Medicine and Health, Statistical source journal of Chinese Academic Journal Impact Factor Annual Report, China Science Citation Database CSCD (1996-2018); Overview of Key Chinese Core Journals of Peking University (1992-2020, 2023-), It has been reported by China Journal Network, China Academic Journals (Optical Disc Edition), China Biomedical Citation Database CMCI, Science and Technology Journals World Impact Index (WJCI) (2022), Wanfang Data Resource System digital Journal Group (China Core Journal Database); American Medical Index (IM), American Chemical Abstracts (CA), etc. Progress in Physiological Sciences is published at home and abroad. The journal comprehensively reports the new progress in physiological sciences at home and abroad, and publishes review papers related to physiological sciences, namely physiology, biochemistry and molecular biology, pharmacology, pathophysiology, biophysics, nutrition, etc.
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