Neurocryptococcosis in immunocompetent patient with psychosis.

Isabelly Sanally Monteiro Florentino, José Brasileiro Dourado Júnior, Amaury Cantilino
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Abstract

Background: The involvement of Cryptococcus as an etiological agent in behavioral disorders, such as psychosis, is rare finding.

Methods: We report the case of 20-year-old man showed apparent functioning behavior premorbid, immunocompetent, with had a first psychotic episode one day after a clinical condition by mild fever, polyarthralgia, headache, fatigue and insomnia and detected cryptococcal antigen latex and India ink positive for Cryptococus neoformans in lumbar puncture. The psychotic episode responded to antifungal and antipsychotic treatment.

Conclusions: We emphasize the importance of paying attention to subtle systemic and neurological signs and investigating the general medical condition cause in the case of a first psychotic episode.

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免疫功能正常的精神病患者患上了神经隐球菌病。
背景:将隐球菌作为行为障碍(如精神病)的病原体是罕见的发现:我们报告了这样一例病例:20 岁男性,病前表现出明显的行为功能,免疫功能正常,在出现轻度发热、多发性关节痛、头痛、乏力和失眠等临床症状一天后首次出现精神病发作,腰椎穿刺检测到隐球菌抗原乳胶和印度墨水阳性。抗真菌和抗精神病治疗后,患者的精神病发作有所好转:我们强调,对于首次精神病发作的病例,必须重视细微的全身和神经系统体征,并调查一般医疗状况的原因。
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Clinical Schizophrenia and Related Psychoses
Clinical Schizophrenia and Related Psychoses Medicine-Psychiatry and Mental Health
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期刊介绍: The vision of the exciting new peer-reviewed quarterly publication Clinical Schizophrenia & Related Psychoses (CS) is to provide psychiatrists and other healthcare professionals with the latest research and advances in the diagnosis and treatment of schizophrenia and related psychoses. CS is a practice-oriented publication focused exclusively on the newest research findings, guidelines, treatment protocols, and clinical trials relevant to patient care.
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