Prevalence and clinical impact of childhood adversities in women with schizophrenia.

Cintia R Prokopez, Oscar M Cesoni, Gabriela B Caporusso, María L Reffino-Pereyra, Germán Alberio, Miguel Vallejos
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Abstract

Patients with schizophrenia have higher rates of adverse childhood experiences (ACEs) than the general population, and those who suffered multiple traumatic experiences have a higher prevalence of positive symptoms, poorer social functioning and more suicidal ideations and behavior. The current study aims to determine the prevalence of ACEs in a female patient sample with schizophrenia. An observational descriptive cross-sectional study was conducted. Participants included 50 female patients older than 18 years, with schizophrenia. Semi-structured interviews and the Adverse Childhood Experiences Questionnaire were conducted. We observed that 90% experienced at least one ACE. Most (52%) suffered 4 or more ACEs. A high prevalence of emotional abuse and neglect was found and a significant relationship between patients who suffered multiple ACEs and the presence of suicidal behavior and persistent auditory hallucinations.

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精神分裂症女性患者童年逆境的发生率和临床影响。
精神分裂症患者的童年不良经历(ACEs)发生率高于普通人群,而遭受过多重创伤经历的患者的阳性症状发生率更高、社会功能更差、自杀意念和行为更多。本研究旨在确定精神分裂症女性患者样本中 ACE 的患病率。本研究是一项观察性描述性横断面研究。研究对象包括 50 名 18 岁以上的女性精神分裂症患者。研究人员对她们进行了半结构式访谈和童年不良经历问卷调查。我们发现,90%的人至少经历过一次童年不良经历。大多数人(52%)经历过 4 次或更多的 ACE。我们发现,情感虐待和忽视的发生率很高,而且经历过多次ACE的患者与自杀行为和持续性幻听之间存在显著关系。
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Clinical Schizophrenia and Related Psychoses
Clinical Schizophrenia and Related Psychoses Medicine-Psychiatry and Mental Health
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期刊介绍: The vision of the exciting new peer-reviewed quarterly publication Clinical Schizophrenia & Related Psychoses (CS) is to provide psychiatrists and other healthcare professionals with the latest research and advances in the diagnosis and treatment of schizophrenia and related psychoses. CS is a practice-oriented publication focused exclusively on the newest research findings, guidelines, treatment protocols, and clinical trials relevant to patient care.
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