[A new cassane diterpene from Caesalpinia bonduc].

药学学报 Pub Date : 2017-02-01

Wen-chao Tu, Lin-fen Ding, Hui Yang, Liu-dong Song, Xing-de Wu

引用次数: 0

Abstract

Five cassane diterpenes were isolated from the 95% ethanol extract of the seeds of Caesalpinia bonduc (Leguminosea) by a combination of various chromatographic methods, including silica gel, Sephadex LH-20, and semi-preparative HPLC. On the basis of spectroscopic techniques, their structures were identified as 3β-acetoxy-cassa-12,14(17),15-trien-7β-ol (1), caesalmin C (2), caesall E (3), caesalpinin MJ (4), and 1-deacetylcaesalmin C (5). Among them, compound 1 is a new compound and 2, 4, 5 were isolated from the plant for the first time.

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【一个新的产于山杨中的cassane二萜】。

采用硅胶、SephadexLH-20、半制备高效液相色谱等多种色谱方法，从豆科植物Caesalpiniabonduc (Leguminosea)种子95%乙醇提取物中分离得到5种木薯烷二萜。通过光谱技术鉴定其结构分别为3β-乙酰氧基木薯-12,14(17)，15-三烯-7β-醇(1)，凯撒碱C(2)，凯撒碱E(3)，凯撒碱MJ(4)和1-去乙酰凯撒碱C(5)，其中化合物1为新化合物，2、4、5为首次从该植物中分离得到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

药学学报 Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Acta Pharmaceutica Sinica B (APSB) is a bimonthly English peer-reviewed online journal in ScienceDirect, which publishes significant original research articles, communications and high quality reviews of recent advances. APSB encourages submissions from all areas of pharmaceutical sciences, including pharmacology, pharmaceutics, medicinal chemistry, natural products, pharmacognosy, pharmaceutical analysis and pharmacokinetics. APSB is a part of the series Acta Pharmaceutica Sinica, which was founded in 1953. The journal is co-published by Elsevier B.V., in association with the Institute of MateriaMedica, Chinese Academy of Medical Sciences and Chinese Pharmaceutical Association.