{"title":"[A new triterpenic acid from the roots of Rosa laevigata].","authors":"Yu-lu Li, Hua-nian Dai, Guo-xu Ma, Wen Zhang, Tong-yu Wu, Yun-qing Wang, Jie-ming Zou, Xiao-qing Zhong, Yan-lin Zhou, Jing-quan Yuan, Xu-dong Xu, Wei Yi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>This study was designed to investigate triterpenoids from the roots of Rosa laevigata Michx.\nThe silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa\nlaevigata Michx. HPLC was used to analyze its purity and chemical constitution. Spectroscopy methods were\nused to determine their structures. Five constituents were isolated and identified as19α-OH-3β-E-feruloyl corosolic\nacid (1), 23-hydroxy-tormentic acid (2), 2α, 3β, 19α, 23- tetrahydroxy-12-en-28-oleanolic acid (3), 2α, 3α, 20β-\ntrihydroxyurs-13 (18)-en-28-oic-acid (4), 2α, 3β, 20β-trihydroxyurs-13 (18)-en-28-oic-acid (5). Compound 1 was\nassigned as a new compound, compounds 4, 5 were obtained from the genus Rosa for the first time.</p>","PeriodicalId":35924,"journal":{"name":"药学学报","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"药学学报","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This study was designed to investigate triterpenoids from the roots of Rosa laevigata Michx.
The silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa
laevigata Michx. HPLC was used to analyze its purity and chemical constitution. Spectroscopy methods were
used to determine their structures. Five constituents were isolated and identified as19α-OH-3β-E-feruloyl corosolic
acid (1), 23-hydroxy-tormentic acid (2), 2α, 3β, 19α, 23- tetrahydroxy-12-en-28-oleanolic acid (3), 2α, 3α, 20β-
trihydroxyurs-13 (18)-en-28-oic-acid (4), 2α, 3β, 20β-trihydroxyurs-13 (18)-en-28-oic-acid (5). Compound 1 was
assigned as a new compound, compounds 4, 5 were obtained from the genus Rosa for the first time.
药学学报Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.20
自引率
0.00%
发文量
0
期刊介绍：
Acta Pharmaceutica Sinica B (APSB) is a bimonthly English peer-reviewed online journal in ScienceDirect, which publishes significant original research articles, communications and high quality reviews of recent advances. APSB encourages submissions from all areas of pharmaceutical sciences, including pharmacology, pharmaceutics, medicinal chemistry, natural products, pharmacognosy, pharmaceutical analysis and pharmacokinetics.
APSB is a part of the series Acta Pharmaceutica Sinica, which was founded in 1953. The journal is co-published by Elsevier B.V., in association with the Institute of MateriaMedica, Chinese Academy of Medical Sciences and Chinese Pharmaceutical Association.
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