Expert Consensus on The Management of Dermatophytosis in India (ECTODERM India).

Q2 Medicine BMC Dermatology Pub Date : 2018-07-24 DOI:10.1186/s12895-018-0073-1
Murlidhar Rajagopalan, Arun Inamadar, Asit Mittal, Autar K Miskeen, C R Srinivas, Kabir Sardana, Kiran Godse, Krina Patel, Madhu Rengasamy, Shivaprakash Rudramurthy, Sunil Dogra
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引用次数: 137

Abstract

Background: Dermatophytosis management has become an important public health issue, with a large void in research in the area of disease pathophysiology and management. Current treatment recommendations appear to lose their relevance in the current clinical scenario. The objective of the current consensus was to provide an experience-driven approach regarding the diagnosis and management of tinea corporis, cruris and pedis.

Methods: Eleven experts in the field of clinical dermatology and mycology participated in the modified Delphi process consisting of two workshops and five rounds of questionnaires, elaborating definitions, diagnosis and management. Panel members were asked to mark "agree" or "disagree" beside each statement, and provide comments. More than 75% of concordance in response was set to reach the consensus.

Result: KOH mount microscopy was recommended as a point of care testing. Fungal culture was recommended in chronic, recurrent, relapse, recalcitrant and multisite tinea cases. Topical monotherapy was recommended for naïve tinea cruris and corporis (localised) cases, while a combination of systemic and topical antifungals was recommended for naïve and recalcitrant tinea pedis, extensive lesions of corporis and recalcitrant cases of cruris and corporis. Because of the anti-inflammatory, antibacterial and broad spectrum activity, topical azoles should be preferred. Terbinafine and itraconazole should be the preferred systemic drugs. Minimum duration of treatment should be 2-4 weeks in naïve cases and > 4 weeks in recalcitrant cases. Topical corticosteroid use in the clinical practice of tinea management was strongly discouraged.

Conclusion: This consensus guideline will help to standardise care, provide guidance on the management, and assist in clinical decision-making for healthcare professionals.

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关于印度皮肤癣管理的专家共识(ECTODERM India)。
背景:皮肤真菌病的管理已成为一个重要的公共卫生问题,在疾病病理生理学和管理领域的研究有很大的空白。目前的治疗建议似乎在当前的临床情况下失去了相关性。目前的共识的目标是提供一个经验驱动的方法,关于癣的诊断和管理,脚癣和足癣。方法:11位临床皮肤科和真菌学专家参与了由2次研讨会和5轮问卷组成的改进德尔菲法,详细阐述了定义、诊断和管理。小组成员被要求在每个陈述旁边标记“同意”或“不同意”,并提供评论。超过75%的回应是一致的,以达成共识。结果:KOH mount镜检被推荐作为护理点检测。对于慢性、复发、复发、顽固性和多部位癣患者,建议进行真菌培养。对于naïve脚癣和体癣(局部)病例,推荐局部单药治疗,而对于naïve和顽固性足癣、广泛的体癣和顽固性脚癣和体癣的病例,推荐全身和局部抗真菌药物联合治疗。由于抗炎、抗菌和广谱活性,局部使用唑类药物是首选。特比萘芬和伊曲康唑应是首选全身用药。naïve病例的最短治疗时间为2-4周,顽固性病例的最短治疗时间为> 4周。局部使用皮质类固醇在临床实践的癣管理是强烈反对的。结论:该共识指南有助于规范护理,指导管理,协助医护人员进行临床决策。
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来源期刊
BMC Dermatology
BMC Dermatology Medicine-Dermatology
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期刊介绍: BMC Dermatology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of skin disorders, as well as related molecular genetics, pathophysiology, and epidemiology. BMC Dermatology (ISSN 1471-5945) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus and Google Scholar.
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