{"title":"[Studies on Chemical Constituents from the Fruit of Swietenia macrophylla].","authors":"Jin-song Liu, Li-li Zhu, Guo-kai Wang, Gang Wang","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To study the chemical constituents from the fruit of Swietenia macrophylla.</p><p><strong>Methods: </strong>The chemical constituents were extracted and isolated by silica gel, Sephadex LH-20. The chemical structures of components were further elucidated by the physicochemical characters and MS,NMR spectral data.</p><p><strong>Results: </strong>17 compounds were isolated and identified as swietenine( 1),swietenine acetate( 2),febrifugine( 3),khayasin T( 4),3-O-tigloyl-6-O-acetylswietenolide( 5),3-O-tigloylswietenolide( 6),3,6-O,O-diacetylswietenolide( 7),fissinolide( 8),3-O-acetylswietenolide( 9), proceranolide( 10),swietenolide( 11),swietemahonin E( 12),swietemahonin F( 13),7-deacetoxy-7-oxogedunin( 14),secomahoganin( 15),altissimanin B( 16),ororatone( 17).</p><p><strong>Conclusion: </strong>Compounds3,5,8 ~ 10,16,17 are isolated from this plant for the first time.</p>","PeriodicalId":15312,"journal":{"name":"中药材","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中药材","FirstCategoryId":"3","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To study the chemical constituents from the fruit of Swietenia macrophylla.
Methods: The chemical constituents were extracted and isolated by silica gel, Sephadex LH-20. The chemical structures of components were further elucidated by the physicochemical characters and MS,NMR spectral data.
目的:研究大叶甜果的化学成分。方法:采用硅胶Sephadex LH-20对其化学成分进行提取和分离。通过理化性质和质谱、核磁共振数据进一步阐明了各组分的化学结构。结果:共分离得到17个化合物，分别鉴定为猪藤碱(1)、猪藤碱醋酸酯(2)、猪藤碱(3)、猪藤碱T(4)、3- o -6- o -乙酰猪藤烯内酯(5)、3- o -o -乙酰猪藤烯内酯(6)、3,6- o -o -二乙酰猪藤烯内酯(7)、鱼藤内酯(8)、3- o -乙酰猪藤烯内酯(9)、原猪藤内酯(10)、猪藤烯内酯(11)、猪藤素E(12)、猪藤素F(13)、7-去乙酰氧猪藤素(14)、猪藤素E(15)、猪藤素B(16)、ororatone(17)。结论:化合物3、5、8 ~ 10、16、17为首次从该植物中分离得到。
期刊介绍：
"Chinese Materia Medica" magazine was founded in 1978. It is a national-level academic journal of Chinese medicine science and technology approved by the State Science and Technology Commission and the Press and Publication Administration for public distribution at home and abroad. It is sponsored by the Chinese Materia Medica Information Center of the State Food and Drug Administration and is publicly distributed at home and abroad. It mainly reports on new technologies, new methods and new achievements in the production, scientific research and business management of Chinese medicine, and serves to promote the production and scientific and technological development of Chinese medicine, improve the output and quality of Chinese medicine, improve business management, and prosper the Chinese medicine industry.
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