High Frequency Acceleration: A New Tool for Alveolar Bone Regeneration.

JSM dental surgery Pub Date : 2017-01-01 Epub Date: 2017-08-25
M Alikhani, C Sangsuwon, S Alansari, J M Nervina, C C Teixeira
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Abstract

Introduction: A common problem in clinical dentistry is the significant and rapid bone loss that occurs after periodontitis, osteoporosis, tooth extractions, lack of function, or any other pathologic condition that target the alveolar bone. Currently there is no stable solution for the long-term preservation or rehabilitation of alveolar bone. In this article, we review the latest concepts on bone response to mechanical stimulation, and summarize the results of our studies on the effect of high frequency acceleration (HFA) on healthy alveolar bone and on healing alveolar bone after extractions.

Methods: In both studies, we used adult Sprague Dawley rats to test the response of alveolar bone to different frequencies and accelerations applied to the maxillary molars.

Results: Once we determined which parameters of HFA induced a higher osteogenic response, we tested the effect of this mechanical stimulation during bone healing after molar extraction. Our studies strongly show that HFA can stimulate bone formation in the healthy alveolar bone surrounding the tooth/point of application as well as the distant bone surrounding the neighboring teeth. When HFA was applied to the second molar, after extraction of the third molar, it accelerated bone healing and prevented alveolar bone resorption in and around the extraction socket.

Conclusion: HFA is a noninvasive safe treatment that can be used to prevent alveolar bone loss, accelerate bone healing and to improve the quality and quantity of alveolar bone under both physiological and pathological conditions.

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高频加速:牙槽骨再生的新工具。
临床牙科的一个常见问题是在牙周炎、骨质疏松、拔牙、功能缺失或任何其他针对牙槽骨的病理情况后发生的显著和快速的骨质流失。目前对于牙槽骨的长期保存和修复尚无稳定的解决方案。本文综述了骨对机械刺激反应的最新概念,并总结了高频加速(HFA)对健康牙槽骨和拔牙后牙槽骨愈合影响的研究结果。方法:在这两项研究中,我们都用成年大鼠测试了牙槽骨对不同频率和加速度施加在上颌磨牙上的反应。结果:一旦我们确定了HFA的哪些参数诱导了更高的成骨反应,我们测试了这种机械刺激在磨牙拔牙后骨愈合过程中的效果。我们的研究有力地表明HFA可以刺激牙齿/应用点周围的健康牙槽骨以及邻近牙齿周围的远端骨的骨形成。当HFA应用于第二磨牙时,第三磨牙拔除后,HFA可加速骨愈合,阻止拔牙槽内及周围的牙槽骨吸收。结论:HFA是一种无创的安全治疗方法,在生理和病理条件下均可预防牙槽骨丢失,加速骨愈合,提高牙槽骨质量和数量。
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High Frequency Acceleration: A New Tool for Alveolar Bone Regeneration.
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