Global role for coactivator complexes in RNA polymerase II transcription.

IF 3.6 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Transcription-Austin Pub Date : 2019-02-01 Epub Date: 2018-10-09 DOI:10.1080/21541264.2018.1521214
Veronique Fischer, Kenny Schumacher, Laszlo Tora, Didier Devys
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引用次数: 17

Abstract

SAGA and TFIID are related transcription complexes, which were proposed to alternatively deliver TBP at different promoter classes. Recent genome-wide studies in yeast revealed that both complexes are required for the transcription of a vast majority of genes by RNA polymerase II raising new questions about the role of coactivators.

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助激活物复合物在RNA聚合酶II转录中的全局作用。
SAGA和TFIID是相关的转录复合物,它们被认为可以在不同的启动子类别上交替传递TBP。最近在酵母中进行的全基因组研究表明,这两种复合物都是RNA聚合酶II转录绝大多数基因所必需的,这就提出了关于共激活因子作用的新问题。
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来源期刊
Transcription-Austin
Transcription-Austin BIOCHEMISTRY & MOLECULAR BIOLOGY-
CiteScore
6.50
自引率
5.60%
发文量
9
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