Adult Onset Henoch-Schonlein Purpura associated with a Metastatic Malignancy of Unknown Primary Origin.

Abstract

The cause of Henoch-Schonlein purpura, or IgA vasculitis, is largely unknown. It has been associated with infections, other rheumatologic triggers, and adverse drug reactions. Rarely, adult Henoch-Schonlein purpura is also associated with solid-tumor malignancies. We present the case of a 66 year-old woman who presented with Henoch-Schonlein purpura associated with a metastatic malignancy of unknown primary origin. We recommend that adult patients presenting with Henoch-Schonlein purpura, especially those with no identifiable trigger, receive age-appropriate work-up for potential malignancy.