[Successful High Flow Nasal Cannula Therapy in a Patient with Myotonic Dystrophy during Perioperative Period].

Satoko Noguchi, Junichi Saito, Masahiro Akaishi, Daichi Ohta, Kazuyoshi Hirota
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Abstract

A 44-year-old woman (body mass index 32) with myotonic dystrophy was admitted for bilateral para- thyroidectomy. Her risk of post-operative respiratory complications was high due to respiratory muscle weakness (%VC 52.8%) and high sputum volume. Difficulties in surgery were anticipated under local anesthesia due to obesity and bilateral tumors. There- fore, general anesthetic management without muscle relaxant was selected and early extubation conducted to prevent respiratory complications. She was extubated 1 hour after surgery in the intensive care unit (ICU) and F10₂ 0.6, 10 l · min⁻¹ oxygen mask was administrated. Paco₂ gradually increased (54 mmHg 15 minutes later, 61 mmHg 2 hours later after extubation). A high flow nasal can- nula was administered to facilitate CO₂ elimination, and Paco₂ decreased to 46 mmHg after 4 hours. An intra- pulmonary percussive ventilator was administered for the purpose of sputum discharge which facilitated effi- cient expectoration of sputum. She was discharged from the ICU on postoperative day (POD) 1 and from hospital on POD 6 without complications.

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[围手术期高流量鼻插管治疗肌强直性营养不良患者的成功案例]。
一位44岁女性(身体质量指数32)因强直性肌营养不良而接受双侧甲状腺旁切除术。术后呼吸肌无力(%VC, 52.8%)及痰量大,呼吸道并发症风险高。由于肥胖和双侧肿瘤,预计局部麻醉下手术困难。因此,选择全麻治疗,不使用肌肉松弛剂,并尽早拔管,以防止呼吸道并发症。术后1小时在重症监护病房(ICU)拔管,给予F10₂0.6,10 l·min(毒血症)氧气面罩。Paco₂逐渐升高(拔管15分钟后为54 mmHg,拔管2小时后为61 mmHg)。给予高流量鼻灌瓶以促进CO₂的消除,4小时后Paco₂降至46 mmHg。采用肺内冲击呼吸机进行痰液排出,使痰液有效排痰。患者于术后第1天出院,第6天出院,无并发症。
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