[Catecholamine Cardiomyopathy Presenting Inverted-takotsubo Pattern Asynergy].

Takuya Okuno, Miki Hino, Ryosuke Kiyama, Kazuo Shindo
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Abstract

Pheochromocytoma is complicated with catecholamine cardiomyopathy, and preoperative care becomes considerably more difficult We report anesthetic management for an 48-year-old man brought to our hospital by ambulance and immediately hospitalized due to pheochromocytoma crisis complicated with catechol- amine cardiomyopathy presenting inverted-takotsubo pattern asynergy. Before surgery, α and β blocking drugs were used to control hypertension and tachycardia, and continuous hemodiafiltration was initiated and the patient was intubated for severe pulmonary edema. Seven days later, he underwent laparoscopic adrenalectomy. Total intravenous anesthesia was achieved with propofol, remifentanil, fentanyl, and rocuronium. During the operation, continuous infusion of landiolol, phentolamine, and nitroglycerin, and addi- tional bolus injections of landiolol were given to control hypertension. After severing the right adrenal vein, noradrenaline (0.15 μg · kg⁻¹ · min⁻¹), and dopamine (4μg · kg⁻¹ · min⁻¹) were started and the patient was placed in the intensive care unit Inverted-takotsubo pattern asynergy is not very common, and treatment consists of supportive care, as in the usual takotsubo. Preoperative CHDF (continuous hemodiafiltration) may be useful when it is difficult to control hypertension or tachycardia with medications.

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[儿茶酚胺性心肌病表现为倒置takotsubo型无能]。
嗜铬细胞瘤合并儿茶酚胺型心肌病,术前护理变得相当困难。我们报告一名48岁男性,因嗜铬细胞瘤危象合并儿茶酚胺型心肌病,表现为倒转takotsubo型无能症,被救护车送到我院并立即住院治疗。术前应用α、β阻断药物控制高血压和心动过速,开始持续血液滤过,严重肺水肿患者插管治疗。7天后,他接受了腹腔镜肾上腺切除术。全静脉麻醉由异丙酚、瑞芬太尼、芬太尼和罗库溴铵完成。术中持续静脉滴注兰地洛尔、酚妥拉明、硝酸甘油,并在此基础上静脉滴注兰地洛尔控制高血压。在切断右肾上腺静脉后,开始使用去甲肾上腺素(0.15 μg·kg⁻¹·min⁻)和多巴胺(4μg·kg⁻¹),并将患者送入重症监护室。倒置的takotsubo模式不常见,治疗包括支持性护理,就像通常的takotsubo一样。术前持续血液滤过(CHDF)在药物难以控制高血压或心动过速时是有用的。
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