Evaluation of neuraxial anesthesia in bearded dragons (Pogona vitticeps)

IF 1.9 2区农林科学 Q2 VETERINARY SCIENCES Veterinary anaesthesia and analgesia Pub Date : 2019-01-01 DOI:10.1016/j.vaa.2018.09.001

Tatiana H. Ferreira, Christoph Mans

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引用次数: 10

Abstract

Objective

To assess the feasibility, success rate, onset, duration and extent of motor/sensory block following intrathecal injection of lidocaine in bearded dragons (Pogona vitticeps).

Study design

Prospective experimental study.

Animals

A group of eight adult bearded dragons (0.333 ± 0.048 kg).

Methods

The animals were sedated with alfaxalone (15 mg kg⁻¹) subcutaneously. Neuraxial injections were performed with 1% lidocaine (2 mg kg⁻¹) or 0.9% sodium chloride (0.2 mL kg⁻¹) in all animals with a 7 day interval. If the initial injection did not result in motor block of the pelvic limbs within 10 minutes, a second injection was performed at the same dose. Measurements consisted of bilateral mechanical stimulation of limbs; 25%, 50%, and 75% of the trunk’s length; and cloacal tone. Animals were monitored for any untoward side effects by monitoring heart rate (HR), respiratory rate, righting reflex and head position.

Results

Success rate following the first injection of lidocaine was 50% (four out of eight animals) and increased to 75% (six out of eight animals) following a second injection. Onset of motor/sensory block occurred within 5 minutes in all successful injections. Duration and extent were variable, with most bearded dragons presenting motor/sensory block of cloaca and pelvic limbs (six out of six) and 25% of the trunk (five out of six) with mean ± standard deviation (range) duration of 49 ± 28 (25–100), 48 ± 25 (25–90) and 40 ± 14 (25–50) minutes, respectively. Confirmation of intrathecal injection by aspiration of cerebrospinal fluid was not possible. Neuraxial lidocaine significantly increased depth and duration of sedation, with a transient increase in HR, compared with saline.

Conclusion and clinical relevance

Neuraxial lidocaine is a feasible technique with moderate success rate and low risk of complication in bearded dragons. This technique has potential for improving the management of anesthesia in this species.

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胡子龙神经轴向麻醉的评价

目的评价胡子龙鞘内注射利多卡因引起运动/感觉阻滞的可行性、成功率、起效、持续时间和程度。研究设计前瞻性实验研究。一组8只成年须龙(0.333±0.048公斤)。方法采用紫杉醇(15 mg kg−1)皮下麻醉。所有动物均接受1%利多卡因(2mg kg - 1)或0.9%氯化钠(0.2 mL kg - 1)的轴向注射，间隔7天。如果第一次注射在10分钟内未引起盆腔肢体运动阻滞，则以相同剂量进行第二次注射。测量包括双侧肢体机械刺激;躯干长度的25%、50%和75%;还有泄殖腔音。通过监测心率(HR)、呼吸频率、翻正反射和头部位置来监测动物是否有不良副作用。结果第一次注射利多卡因后成功率为50%(8只动物中4只)，第二次注射后成功率为75%(8只动物中6只)。所有成功注射的患者均在5分钟内出现运动/感觉阻滞。持续时间和程度各不相同，大多数胡须龙表现为泄殖腔和盆腔肢体的运动/感觉阻塞(6 / 6)和躯干的25%(5 / 6)，平均±标准偏差(范围)持续时间分别为49±28(25 - 100)，48±25(25 - 90)和40±14(25 - 50)分钟。通过抽吸脑脊液来确认鞘内注射是不可能的。与生理盐水相比，轴向利多卡因显著增加了镇静的深度和持续时间，HR短暂增加。结论及临床意义利多卡因静脉注射是一种可行的治疗方法，成功率中等，并发症发生率低。这项技术有潜力改善该物种的麻醉管理。

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来源期刊

Veterinary anaesthesia and analgesia 农林科学-兽医学

CiteScore

3.10

自引率

17.60%

发文量

审稿时长

97 days

期刊介绍： Veterinary Anaesthesia and Analgesia is the official journal of the Association of Veterinary Anaesthetists, the American College of Veterinary Anesthesia and Analgesia and the European College of Veterinary Anaesthesia and Analgesia. Its purpose is the publication of original, peer reviewed articles covering all branches of anaesthesia and the relief of pain in animals. Articles concerned with the following subjects related to anaesthesia and analgesia are also welcome: the basic sciences; pathophysiology of disease as it relates to anaesthetic management equipment intensive care chemical restraint of animals including laboratory animals, wildlife and exotic animals welfare issues associated with pain and distress education in veterinary anaesthesia and analgesia. Review articles, special articles, and historical notes will also be published, along with editorials, case reports in the form of letters to the editor, and book reviews. There is also an active correspondence section.