Postoperative swallowing disorder after thyroid and parathyroid resection.

IF 2.3 Q2 MEDICINE, GENERAL & INTERNAL Pragmatic and Observational Research Pub Date : 2018-10-16 eCollection Date: 2018-01-01 DOI:10.2147/POR.S172059
Andreas Hillenbrand, Gregor Cammerer, Lisa Dankesreiter, Johannes Lemke, Doris Henne-Bruns
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引用次数: 9

Abstract

Introduction: Dysphagia is frequently reported after thyroidectomy. Here, we investigated the incidence of postoperative dysphagia after uncomplicated thyroidectomy and parathyroidectomy. Further, we analyzed diagnosis and types of therapy to identify possible patients at risk.

Patients and methods: A questionnaire was sent to 372 consecutive patients whose thyroid or parathyroid glands were operated on between May 2013 and October 2014 at Ulm University Hospital. Patients were questioned at least 6 months postoperatively.

Results: In the evaluation, 219 questionnaires could be included. Fifty-three (21.3%) patients reported that the overall postoperative swallowing process was better or more trouble-free. In 110 (50.2%) patients, dysphagia was reported only immediately postoperative and disappeared later spontaneously. Sixteen patients (7.3%) stated that after a maximum of 3 months after surgery they suffered from dysphagia. One (0.5%) patient stated that up to 3 months postoperatively, swallowing problems had been successfully treated by logopedic therapy. In 39 (17.6%) patients, the complaints persisted for more than 3 months or still existed at the time of the interview. We found no correlation between dysphagia and patients' age or gender, the specimen volume, and patients' body mass index. The more invasive the operation was, the more patients suffered from dysphagia. Analyzing the frequency of dysphagia according to different diagnoses, we found a significant risk of postoperative dysphagia in patients with Graves' disease and carcinoma. Patients operated on for hyperparathyroidism were at significantly decreased risk of dysphagia.

Conclusion: Nearly 20% of patients reported postoperative dysphagia after uncomplicated thyroidectomy and parathyroidectomy, especially after major surgical intervention. We found a significant risk of postoperative dysphagia in patients with Graves' disease and carcinoma and a decreased risk for patients operated on for hyperparathyroidism.

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甲状腺及甲状旁腺切除术后吞咽障碍。
摘要:吞咽困难是甲状腺切除术后常见的症状。在这里,我们调查了单纯甲状腺切除术和甲状旁腺切除术后吞咽困难的发生率。此外,我们分析了诊断和治疗类型,以确定可能存在风险的患者。患者和方法:对2013年5月至2014年10月在乌尔姆大学医院连续行甲状腺或甲状旁腺手术的372例患者进行问卷调查。患者在术后至少6个月接受问询。结果:评估共纳入问卷219份。53例(21.3%)患者报告术后整体吞咽过程更好或更无故障。110例(50.2%)患者术后立即出现吞咽困难,随后自行消失。16例患者(7.3%)表示在术后最多3个月后出现吞咽困难。一名(0.5%)患者表示,术后3个月,吞咽问题已通过喉道治疗成功解决。39例(17.6%)患者的抱怨持续3个月以上或在访谈时仍存在。我们发现吞咽困难与患者的年龄或性别、标本体积和患者的体重指数之间没有相关性。手术侵入性越强,患者出现吞咽困难的几率越大。根据不同的诊断分析吞咽困难的频率,我们发现Graves病和癌患者术后出现吞咽困难的风险显著。手术治疗甲状旁腺功能亢进的患者发生吞咽困难的风险显著降低。结论:无并发症甲状腺切除术和甲状旁腺切除术后,有近20%的患者报告术后吞咽困难,特别是在大手术干预后。我们发现Graves病和癌患者术后吞咽困难的风险显著,甲状旁腺功能亢进患者术后吞咽困难的风险降低。
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Pragmatic and Observational Research
Pragmatic and Observational Research MEDICINE, GENERAL & INTERNAL-
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期刊介绍: Pragmatic and Observational Research is an international, peer-reviewed, open-access journal that publishes data from studies designed to closely reflect medical interventions in real-world clinical practice, providing insights beyond classical randomized controlled trials (RCTs). While RCTs maximize internal validity for cause-and-effect relationships, they often represent only specific patient groups. This journal aims to complement such studies by providing data that better mirrors real-world patients and the usage of medicines, thus informing guidelines and enhancing the applicability of research findings across diverse patient populations encountered in everyday clinical practice.
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